Acquired ichthyosis: a clinical review

Haber, Richard M.; Feghali, Joëlle Ann; Nadir, Umer; Yi, Michael D.; Cahn, Brian A.

doi:10.1007/s00403-023-02668-5

Cited by 2 publications

(1 citation statement)

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“…Acquired ichthyosis and erythema gyratum repens have been reported as two paraneoplastic skin disorders present in the same patient with transitional cell carcinoma [96]. From case reports and observational studies, it has been noted that erythema gyratum repens precedes the diagnosis of malignancy, while acquired ichthyosis occurs before, simultaneously, or after the onset of malignancy [97]. The appearance of two paraneoplastic skin disorders in the same patient can be explained by the secretion of TNF-alpha by tumor cells, which has been shown to be a mitogen for keratinocytes [96,98].…”

Section: Paraneoplastic Syndromes In Rccmentioning

confidence: 99%

The Cellular Stress and Cutaneous Manifestations in Renal Cell Carcinomas—A Narrative Review

Ene,

Nicolae,

Tampa

et al. 2024

JCM

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The carcinomas originating from the renal cortex are the most aggressive renal malignancies, with a high tendency for metastasis. Understanding the incidence of cutaneous manifestations caused by renal carcinomas is a challenge. In the first part, this article summarizes a series of factors that promote oncogenesis, invasiveness, and the ability of renal cell carcinoma (RCC) to develop secondary cutaneous manifestations. It is postulated that the cellular stress response is one of the leading causes of developing dermatological events induced by cancers located at distant sites. Furthermore, the paper provides an overview of cutaneous complications associated with renal cancer, categorized as malignant manifestations (metastases, synchronous or metachronous cutaneous malignancies associated with renal cancer), non-malignant indirect cutaneous manifestations associated with renal cancer, and treatment consequences. The data presented in this article suggest that recognizing certain cutaneous disorders could assist the physician in the early identification of renal neoplasms and could lead to a better prognosis.

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