Wearable diagnostic system for age-related macular degeneration

Abstract

This paper presents a novel head-mounted point-of-care diagnostic system for detection and continuous monitoring of Age-related Macular Degeneration (AMD). This wearable embedded open-source platform enables accurate monitoring of AMD by taking advantage of multiple standard graphical interface techniques such as Amsler Grid, Threshold Amsler Grid, Macular Computerized Psychophysical Test and Preferential Hyperacuity Perimeter (PHP). Here, we describe the proposed multi-Grid or so-called NGRID software and elaborate on the hardware prototype. This prototype includes a commercially available Oculus HMD incorporated with a single board computer. As the first step towards a fully integrated wearable system, this paper successfully proves the functionality of head-mounted graphical interface device ready for a live demonstration. Participants can experience this device and take a 10-minute AMD eye-exam. Furthermore, NGRID has been approved and permitted for an in-hospital clinical trial.

Recent Advances of Computerized Graphical Methods for the Detection and Progress Assessment of Visual Distortion Caused by Macular Disorders

“…The static VD assessment methods suffer from the filling and crowding effect due to the similarity of stimulation patterns. We have recently addressed this issue by proposing a novel method called NGRID [41,42,43]. In this method, instead of one grid such as Amsler grid or another type of pattern, a number of different patterns are projected on the patient’s retina.…”

Head-mounted digital metamorphopsia suppression as a countermeasure for macular-related visual distortions for prolonged spaceflight missions and terrestrial health

“…As such, there is a direct need for accessible solutions to help rehabilitate and reduce the effects of vision loss from macular disruptions. Given its accessibility and portability components, wearable head-mounted technology has emerged as a promising innovation for terrestrial ophthalmic disorders including AMD, glaucoma, and amblyopia (Mohaghegh et al, 2016 ; Miao et al, 2020 ; Stapelfeldt et al, 2021 ). In the following sections, we detail the development of a head-mounted, digital suppression as a potential countermeasure for macular-related visual distortions.…”