Recent Advances of Computerized Graphical Methods for the Detection and Progress Assessment of Visual Distortion Caused by Macular Disorders

Mohaghegh, Navid; Ghafar-Zadeh, Ebrahim; Magierowski, Sebastian

doi:10.3390/vision3020025

Cited by 3 publications

(2 citation statements)

References 52 publications

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“…These patients can have various stages of nonneovascular AMD Newer methods for evaluation of metamorphopsia exist, including computerized and smartphone application-based techniques with static or dynamic testing principles. 28 The dominant principle in dynamic testing is hyperacuity, and currently, commercially available devices include the Foresee-Home monitor (Notal Vision Inc) and the Alley (Oculocare) and myVisionTrack (Vital Art and Sc ience) smartphone applications. [29][30][31] These methods have shown some promise but are not without limitations.…”

Section: Discussionmentioning

confidence: 99%

Diagnostic Accuracy of the Amsler Grid Test for Detecting Neovascular Age-Related Macular Degeneration

et al. 2023

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ImportancePatients with nonneovascular age-related macular degeneration (AMD) are encouraged to use the Amsler grid test for self-assessment to facilitate early diagnosis. The test is widely recommended, suggesting a belief that it signals worsening AMD, warranting its use in home monitoring.ObjectiveTo systematically review studies of the diagnostic test accuracy of the Amsler grid in the diagnosis of neovascular AMD and to perform diagnostic test accuracy meta-analyses.Data SourcesA systematic literature search was conducted in 12 databases for relevant titles from database inception until May 7, 2022.Study SelectionStudies included those with groups defined as having (1) neovascular AMD and (2) either healthy eyes or eyes with nonneovascular AMD. The index test was the Amsler grid. The reference standard was ophthalmic examination. After removal of obviously irrelevant reports, 2 authors (J.B. and M.S.) independently screened the remaining references in full text for potential eligibility. Disagreements were resolved by a third author (Y.S.).Data Extraction and SynthesisTwo authors (J.B. and I.P.) independently extracted all data and evaluated quality and applicability of eligible studies using the Quality Assessment of Diagnostic Accuracy Studies 2. Disagreements were resolved by a third author (Y.S.).Main Outcomes and MeasuresSensitivity and specificity of the Amsler grid for detecting neovascular AMD with comparators being either healthy control participants or patients with nonneovascular AMD.ResultsOf 523 records screened, 10 studies were included with a total of 1890 eyes (mean participant age ranging from 62 to 83 years). Sensitivity and specificity to diagnose neovascular AMD were 67% (95% CI, 51%-79%) and 99% (95% CI, 85%-100%), respectively, when comparators were healthy control participants and 71% (95% CI, 60%-80%) and 63% (95% CI, 49%-51%), respectively, when control participants were patients with nonneovascular AMD. Overall, potential sources of bias were low across studies.Conclusions and RelevanceAlthough the Amsler grid is easy and inexpensive to use for detection of metamorphopsia, its sensitivity may be at levels typically not recommended for monitoring. Coupling this lower sensitivity with only moderate specificity to identify neovascular AMD in a population at risk, these findings suggest that such patients typically should be encouraged to undergo ophthalmic examination regularly, regardless of any results of Amsler grid self-assessment.

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Section: Discussionmentioning

confidence: 99%

Diagnostic Accuracy of the Amsler Grid Test for Detecting Neovascular Age-Related Macular Degeneration

et al. 2023

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“…Current methods of home monitoring in ophthalmology including the Amsler grid and personal device applications such as smartphones and tablets face similar challenges with patient compliance, and also challenges related to reliable use and low-sensitivity for visual changes. 33 , 46 , 47 Nevertheless, technology development is a continuous process, and next generation devices and new technologies such as incorporation of OCT 48 , 49 into home monitoring systems promise to improve upon the difficulties encountered with current technology and may ultimately transform the way patients are diagnosed and managed. An important trait of home OCT technology is that the assessment of meaningful change will be passive following patient initiation of the at-home test.…”

Section: Discussionmentioning

confidence: 99%

Home Monitoring of Age-Related Macular Degeneration

Kiernan

Eichenbaum

et al. 2021

Ophthalmology Retina

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Purpose To evaluate real-world utility of the ForeseeHome monitoring device for the detection of conversion from intermediate age-related macular degeneration (iAMD) to neovascular AMD (nAMD) and compare with results published by the HOME study. Design Retrospective analysis of electronic health records. Subjects Eyes prescribed use of the ForeseeHome device across 4 retinal practices in the USA. Methods Usage information was collected from the online ForeseeHome portal for all eyes prescribed. For a pre-determined subset of eyes, additional clinical information was collected through chart review and analyzed for clinical utility. Main Outcome Measures Outcome measures include frequency and length of use, number of eyes that used the device, established baseline and converted to nAMD, and number of alerts. Results 775 eyes of 448 patients were prescribed use of the ForeseeHome device. 649 eyes (83.7%) used the device at least once; among this population, 478 (73.7%) established baseline. Patients who established baseline were significantly younger than those who did not establish baseline (p<0.001). Among eyes that established baseline, 126 (26.4%) had an overall inadequate frequency of use (≥2 tests per week), and 250 (52.3%) did not use the device as frequently as instructed by the manufacturer (≥3 tests per week); 112 (24.7%) discontinued use within one year. Over a mean of 20.35 months, 106 patients had 152 alerts, indicating possible conversions to nAMD. Out of the 136 eyes that established baseline among 211 eyes prescribed the device at one clinical site, 52 alerts were recorded, 3 (6.8%) correctly identified conversion to nAMD and 47 (93.2%) represented false-positive alerts. Conclusions Compared to the prospective HOME study, utility of the ForeseeHome device in the current analysis of real-world clinical-practice application was limited. A meaningful proportion of eyes never used the device or could not establish baseline. Overall frequency of use was low and continuous usage of the device decreased over time. There is a need for improvement in home monitoring technology for eyes with iAMD at risk of conversion to nAMD.

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Teleglaucoma: Tools for Enhancing Access to Glaucoma Care for At-Risk and Underserved Populations

Tanya

Giorgis

Marco

et al. 2023

Digital Eye Care and Teleophthalmology

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Recent Advances of Computerized Graphical Methods for the Detection and Progress Assessment of Visual Distortion Caused by Macular Disorders

Cited by 3 publications

References 52 publications

Diagnostic Accuracy of the Amsler Grid Test for Detecting Neovascular Age-Related Macular Degeneration

Diagnostic Accuracy of the Amsler Grid Test for Detecting Neovascular Age-Related Macular Degeneration

Home Monitoring of Age-Related Macular Degeneration

Teleglaucoma: Tools for Enhancing Access to Glaucoma Care for At-Risk and Underserved Populations

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