Outbreak of pasteurellosis in captive Bolivian squirrel monkeys (<i>Saimiri boliviensis</i>)

Abstract

In September 2012, five Bolivian squirrel monkeys housed in a zoological park died within sequential several days without obvious clinical signs. In a necrospy, one monkey presented swelling of the kidney with multifocal white nodules in the parenchyma, and other two had pulmonary congestion. Histopathologically, multifocal bacterial colonies of gram-negative coccobacillus were found in the sinusoid of the liver in all monkeys examined (Nos.1−4). Additionally, purulent pyelonephritis, pneumonia and disseminated small bacterial colonies in blood vessels were observed. Immunohistochemically, the bacterial colonies from two monkeys were positive for P. multocida capsular serotype D. Based on these findings, these monkeys were diagnosed as septicemia caused by acute P. multocida infection.

Draft Genome Sequence of a Pasteurella multocida Strain Isolated from a Spotted Deer (Axis axis) in India

“…In livestock, mainly cattle and buffaloes, P. multocida is one of the common bacteria associated with an economically important production disease, bovine respiratory disease complex, and highly lethal hemorrhagic septicemia ( 1 , 2 ). There are several sporadic reports of P. multocida in wild animals, including spotted deer and leopards ( 3 – 6 ). Although several conventional and molecular typing methods, such as enterobacterial repetitive intergenic consensus (ERIC)/repetitive extragenic palindromic (REP)/randomly amplified polymorphic DNA (RAPD) PCR, Southern blot hybridization, pulse field gel electrophoresis (PFGE), and multilocus sequence typing (MLST) have been largely used in outbreak investigations, very few attempts have been made to sequence the whole genome of a P. multocida strain from wild animals ( 7 , 8 ).…”