A New Approach for the Treatment of Lateral Periodontal Cysts with an 810-nm Diode Laser

Isola, Gaetano; Matarese, Giovanni; G, Lo Giudice; Briguglio, Francesco; Alibrandi, Angela; Crupi, Andrea; Cordasco, Gennaro; Ramaglia, Luca

doi:10.11607/prd.2981

Cited by 28 publications

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“…(3) presence of at least ≥2 mm of crestal alveolar bone loss verified on digital periapical radiographs; (4) presence of ≥40% sites with bleeding on probing (BOP) [21,22]; and (5) no systemic diseases. By considering the new classification of periodontal disease [18], periodontitis patients could be classified as stage 1, grade B, generalized periodontitis patients.…”

Section: Patientsmentioning

confidence: 99%

Periodontitis and Tooth Loss Have Negative Systemic Impact on Circulating Progenitor Cell Levels: A Clinical Study

Isola

Giudice

Alibrandi

et al. 2019

Genes

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The aim of the present study was to investigate the association and impact of periodontitis and tooth loss on a subtype of endothelial progenitor cell (EPC) levels (CD133+/KDR+). Furthermore, the objective was to determine if the periodontal status influenced CD133+/KDR+ levels. In all, 88 patients with periodontitis and 79 healthy controls (HCs) were enrolled in the study. Enrolled patients were examined and characterized by clinical and blood sample analysis. Spearman’s correlation test was applied in order to assess the interdependence between CD133+/KDR+ levels and all periodontal parameters. In order to estimate a statistically significant trend (p-trend) for ordered CD133++/KDR+ quartiles, the Jonckheere–Terpstra test was applied for all variables. Patients in the periodontitis group presented significantly lower CD133+/KDR+ levels (66.4 (45.5–269.6 cells/µL)) compared to the HC group (76.7 (24.3–313.2 cells/µL), p < 0.001). Lower CD133+/KDR+ levels negatively correlated with C-reactive protein (CRP), with the number of teeth, and with all periodontal parameters (p < 0.001). Moreover, there was a proportional increase in CD133+/KDR+ levels with a progressive increase in number of teeth (p-trend < 0.001), while there was a proportional decrease in CD133+/KDR+ levels with a proportional increase in clinical attachment level (CAL, p-trend = 0.003), probing depth (PD, p-trend = 0.007), and bleeding sites (bleeding on probing (BOP), p-trend < 0.001) as an extent measure of periodontitis. This study demonstrated that patients with periodontitis presented significantly lower CD133+/KDR+ levels compared to HCs. Moreover, all patients presented an increase in the CD133+/KDR+ EPC levels with an extended level of periodontitis and tooth loss.

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Section: Patientsmentioning

confidence: 99%

Periodontitis and Tooth Loss Have Negative Systemic Impact on Circulating Progenitor Cell Levels: A Clinical Study

Isola

Giudice

Alibrandi

et al. 2019

Genes

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“…Recently, low-level laser therapy (LLLT) has been shown to be effective in inducing remodeling processes in the soft and hard oral tissues, healing through its photobiostimulation effects [18,19].…”

Section: Introductionmentioning

confidence: 99%

Effectiveness of Low-Level Laser Therapy during Tooth Movement: A Randomized Clinical Trial

et al. 2019

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The present study evaluated the effects of low-level laser therapy (LLLT) by means of a diode laser in accelerating orthodontic tooth movement (OTM). After extraction of the first upper premolars for orthodontic purpose, 82 maxillary canines which needed distalization were analyzed in 41 enrolled patients (21 males, 20 females, mean age 13.4 ± 2.1 years). On all experimental sites, an orthodontic force of 50/N was applied by a nickel-titanium (NiTi) closed coil spring (G&H, Franklin, IN, USA) in order to obtain the space closure. Using a split mouth randomized design, the test side was treated using a diode laser (Wiser Laser Doctor Smile, Brendola, Italy) operating at 810 nm wavelength in continuous wave mode at both the buccal and palatal side on three points/side (distal, medial and mesial) (1 W output power, continuous wave of 66.7 J/cm2, energy density of 8 J) at baseline and at 3, 7, and 14 days and every 15 days until the space closed. On the control side, the opposite selected canine was treated only using orthodontic traction. The primary outcome chosen was the overall time needed to complete the levelling and closing space, measured on a study cast. The secondary outcome chosen was the evaluation of pain levels related to tooth traction, using a Visual Analogue Scale (VAS), recorded at 3, 7, and 14 days after treatments. The mean space closures of the maxillary canines were comparable between groups [Test, 4.56 mm (95% CI 3.9–4.8); Control, 4.49 mm (95% CI 3.8–4.7), p = 0.456]. The laser group yielded less mean time [84.35 ± 12.34 days (95% CI 79.3–86)] to accomplish space closure compared to the control group [97.49 ± 11.44 days (91.7–102.3)] (p < 0.001). The test side showed a significant reduction in the average range of dental pain at 3 [Test, 5.41 (95% CI 5.1–5.6); Control, 7.23 (95% CI 6.9–7.6), p < 0.001], 7 [Test, 4.12 (95% CI 3.8–4.7); Control, 5.79 (95% CI 5.4–5.8), p < 0.001], and at 14 days [Test, 2.31 (95% CI 1.8–2.3); Control, 3.84 (95% CI 3.3–4.2), p < 0.001] after treatment (p < 0.001). This study demonstrates that the use of LLLT therapy was effective in accelerating tooth movement and reducing pain levels related to OTM.

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“…1,2 The introduction of laser-assisted surgery in general dentistry, periodontology, and oral surgery, in view of the excellent performance for the excision of oral tissues, hemostatic action, and faster healing, turned out as a real revolution in the surgical management of GO and also in the postsurgical maintenance of good periodontal status in such patients. 3,4 Recent published studies confirm the therapeutic effects of laser therapy as an adjunct to conventional scaling and root planing in the treatment of aggressive periodontitis in terms of a significant reduction in some clinical parameters 5 ; in addition, also in the management of periodontal conditions needing bone and gingival remodeling, such as surgical crown lengthening, 6 or needing bone, radicular cementum, and soft tissue debridement as in the case of lateral periodontal cysts, 7 resulting in the diode laser treatment in a shorter wound-healing period.…”

Section: Introductionmentioning

confidence: 91%

Nonsurgical Periodontal Treatment by Erbium:YAG Laser Promotes Regression of Gingival Overgrowth in Patient Taking Cyclosporine A: A Case Report

Capodiferro

Tempesta

Limongelli

et al. 2019

Photobiomodulation, Photomedicine, and Laser Surgery

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Objective and background: To report on a case of cyclosporine A-related gingival overgrowth (GO) treated by conventional scaling and Erbium:YAG laser that unexpectedly showed complete healing with normalization of the gingiva, making unnecessary further surgical treatment for gingival volume reduction. Since Erbium:YAG laser was approved in 1997 by the U.S. Food and Drug Administration for hard and soft tissue treatments in dentistry, several studies have been published to demonstrate its efficacy for bone cutting, plaque and subgingival calculus removal, and antiseptic effects both on soft and hard periodontal tissues. Methods: We report herewith the case of a patient undergoing cyclosporine A therapy, affected by GO who underwent scaling and full mouth disinfection with chlorhexidine 2% rinses, followed by Erbium:YAG laser treatment of gingival pseudopockets, without surgical removal of the overgrown gingiva. Results: Unexpectedly, complete healing of the periodontal tissues was observable after one single laser application and no adjunctive surgical procedure was necessary. Conclusions: Erbium:YAG laser could be considered a really effective option for the nonsurgical treatment of drug-induced GO, avoiding the surgical procedures and also promoting a fast healing and a patient compliance surely higher than conventional techniques.

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A New Approach for the Treatment of Lateral Periodontal Cysts with an 810-nm Diode Laser

Cited by 28 publications

References 0 publications

Periodontitis and Tooth Loss Have Negative Systemic Impact on Circulating Progenitor Cell Levels: A Clinical Study

Periodontitis and Tooth Loss Have Negative Systemic Impact on Circulating Progenitor Cell Levels: A Clinical Study

Effectiveness of Low-Level Laser Therapy during Tooth Movement: A Randomized Clinical Trial

Nonsurgical Periodontal Treatment by Erbium:YAG Laser Promotes Regression of Gingival Overgrowth in Patient Taking Cyclosporine A: A Case Report

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