Choice of marker for assessment of RV dysfunction in acute pulmonary embolism

Ateş, Hale; Ateş, İhsan; Kundi, Harun; Yılmaz, Fatma Meriç

doi:10.1007/s00059-016-4513-6

Cited by 5 publications

(2 citation statements)

References 27 publications

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“…The mean age of non-survivors was signi cantly higher than that of survivors (70.2 ± 15.6 years vs. 63.1 ± 18.8 years; p = 0.01). Tachypnoea, haemoptysis, and deep vein thrombosis were more frequent in non-survivors (40, 11, and 38%, respectively) than in survivors (18,4, and 23%, respectively). Furthermore, pregnancy, heart failure, and immobilisation were more frequent in non-survivors (3, 23, and 23%, respectively) than in survivors (1, 15, and 10%, respectively).…”

Section: Resultsmentioning

confidence: 91%

“…Following de nitive diagnosis in the emergency department, it is critical that high-risk patients are referred to the ICU immediately where appropriate treatment can be initiated [16]. Risk classi cation is useful for patients admitted to the ICU because it facilitates the recommendation for an intensive and multidisciplinary follow-up, which may improve the outcome and long-term quality of life in these patients [17,18]. As such, there is a need for readily accessible, simple, and inexpensive scoring systems with high prognostic value.…”

Section: Discussionmentioning

confidence: 99%

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MELD-Albumin score predicts 30-day mortality in high-risk patients with acute pulmonary embolism admitted to intensive care units

İdin¹,

Dereli²,

Yenerçağ³

et al. 2020

Preprint

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Background: The Model for End-stage Liver Disease excluding the international normalised ratio (INR, MELD-XI) and modified MELD, which uses albumin in place of the INR (MELD-Albumin) scores reflect liver and renal function and are predictors of mortality. However, their prognostic value in acute pulmonary embolism (APE) has not been studied.Methods: We assessed the predictive value of the MELD scores in patients diagnosed with high-risk APE admitted to the intensive care unit (ICU). The primary outcome was 30-day mortality.Results: Of the 273 patients included in the study, 231 were survivors and 42 were non-survivors. The mortality rate was 15.3%. The mean Meld-XI and MELD-Albumin scores were significantly higher in the non-survivors than in the survivors (MELD XI, 11.8 ± 1.8 and 10.6 ± 1.43, respectively; p = 0.002; MELD-Albumin, 10.5 ± 1.6 and 8.7 ± 1.1, respectively; p = 0.001). The multiple logistic regression analysis identified the MELD-XI (hazard ratio [HR]: 3.029, confidence interval [CI]: 1.06–1.21, p = 0.007) and MELD-Albumin (HR: 1.13, CI: 1.06–1.21, p = 0.002) scores as independent predictors of mortality. Receiver operating characteristic analysis revealed that the predictive power of the MELD-Albumin score (0.871 ± 0.014; p < 0.001) was higher than those of the MELD-XI (0.726 ± 0.022, p < 0.001), APACHE III (0.682 ± 0.024, p < 0.001), and PESI (0.624 ± 0.023, p < 0.001) scores.Conclusions: The MELD-Albumin score is an easily calculable, reliable, and practical risk assessment tool and independent predictor of 30-day mortality in patients with high-risk APE.

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Section: Resultsmentioning

confidence: 91%

Section: Discussionmentioning

confidence: 99%