Peritoneal tuberculosis is a disease which can mimick malignancy especially in women who present with ascites and elevated CA125 levels. It should always be considered in differential diagnosis, but the diagnosis is rarely easy for clinicians. A young female patient who presented with abdomen tenderness and diagnosed with peritoneal tuberculosis as a result of performed tests is discussed hereby in the case report. We expect that this case report adds to the existing literature on this subject.
SummaryHypothyroidism is a wide clinical spectrum disorder and only a few cases in
literature show this. Rhabdomyolysis and acute renal impairment can be seen
concurrently in a hypothyroid state. We report a case of severe hypothyroidism with
poor drug compliance leading to rhabdomyolysis and acute kidney injury.Learning points:Hypothyroidism is a rare cause of acute kidney injury.In this case report, we studied a rare occurrence of acute renal impairment
due to hypothyroidism with poor drug compliance, which induced
rhabdomyolysis.Our report emphasized that thyroid status should be evaluated in patients
with unexplained acute renal impairment or presenting with the symptoms of
muscle involvement.
Background
Limited data are available concerning the contribution of drugs with anticholinergic properties (DAPs) to undernutrition among older adults. This study aimed to determine the potential association of anticholinergic burden (ACB) to nutrition status in older people.
Methods
We prospectively enrolled participants aged over 65 who underwent a comprehensive geriatric assessment between January 2017 and June 2020. Nutrition status was assessed by the Mini Nutritional Assessment–Short Form (MNA‐SF). The ACB was assessed using the ACB scale.
Results
A total of 615 participants were included in the analysis (mean age ± SD, 78.5 ± 6.6 years; male, 55.3%). The prevalence of undernutrition (MNA‐SF score <12) was 22.6% (n = 139). Participants with undernutrition were predominantly older (P < 0.001), had lower mean body mass index scores (undernutrition, 27.3 ± 5.4 vs healthy, 29.5 ± 8.0; P = 0.007), had a lower educational level (P = 0.016), had higher cardiovascular disease morbidity (P < 0.001), and had a higher ACB (P < 0.001) when compared with those with normal nutrition status. In adjusted analysis, the odds of having undernutrition were higher among participants with an ACB score >1 (odds ratio, 1.20; 95% CI, 1.01–1.43; P = 0.044). The weighted multivariate linear regression analysis showed a significant inverse association between the total ACB score and MNA‐SF score controlling for multiple confounders.
Conclusion
ACB appears to be inversely correlated with nutrition status among older adults. Undernutrition may be considered an additional reason to consider deprescribing DAPs in this population.
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