A review of melasma treatment focusing on laser and light devices

Li, Janet Y.; Geddes, Elizabeth R.; Robinson, Deanne Mraz; Friedman, Paul M.

doi:10.12788/j.sder.2016.060

Cited by 23 publications

(15 citation statements)

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“…Melasma, a common chronic disorder of hyperpigmentation, is often observed in women and appears as hyperpigmented tan to brown macules and patches in malar, centrofacial, and mandibular areas of the face. 1,2 The set of factors that shares in the pathogenesis of melasma remains to be fully investigated, but current research suggests that it is a multifactorial condition. 3 Melasma is a difficult-to-manage disorder with common relapsing behavior.…”

Section: Introductionmentioning

confidence: 99%

Dermoscopy as a useful tool for evaluating melasma and assessing the response to 1064‐nm Q‐switched Nd: YAG laser

Hay

Mohammed

Sayed

et al. 2020

Dermatologic Therapy

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Melasma is a hard‐to‐manage disorder with considerable relapsing behavior. Dermoscopy emerged to help in comprehensive evaluation of pigmentary disorders and melasma. The aim of the study was to evaluate the potential role of dermoscopy in assessing melasma and monitoring the efficacy of 1064‐nm low‐fluence Q‐switched neodymium:yttrium‐aluminum‐garnet (QS Nd:YAG) laser. A total of 31 patients with facial melasma were included. A total of five laser sessions were performed with 2‐week intervals. Patients were evaluated at baseline and 2 weeks after the last session (at the 10th week) by using digital photography, modified melasma area and severity index (mMASI), and colorimetry, as well as dermoscopic score for pigment and vascular elements. Adverse effects were reported. Postlaser sessions, mMASI scores as well as the colorimetric melanin and erythema indices had showed significant improvement. The “dermoscopic score of pigmentary and vascular elements” displayed significant change and confirmed the improvement. Side effects were tolerable. mMASI, colorimetry, and dermoscopy had ascertained the efficacy of low‐fluence 1064‐nm QS Nd:YAG laser in melasma; however, dermoscopy is superior to other assessments as it can help in the diagnosis of melasma besides the follow‐up assessment and can precisely detect the detailed changes in response to treatment.

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Section: Introductionmentioning

confidence: 99%

Dermoscopy as a useful tool for evaluating melasma and assessing the response to 1064‐nm Q‐switched Nd: YAG laser

Hay

Mohammed

Sayed

et al. 2020

Dermatologic Therapy

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“…As the epidermal melanin content is high in Asian skin, adverse pigmentary effects are more likely to occur after laser treatment [1,24]. PIH increases pigmentation secondary to an acquired inflammatory process, which occurs more easily in FSPTs III and VI and can have a considerable effect on quality of life [25].…”

Section: Discussionmentioning

confidence: 99%

“…PIH is a hyperpigmentation disorder resulting from cutaneous inflammation due to acquired inflammatory skin disease, contact with allergens or irritants, cosmetic procedures, or traumatic skin injury [1,6]. Clinical visual assessment by comparison with the normal skin color (at baseline) and history-taking are usually performed with PIH patients [6].…”

Section: Post-inflammatory Hyperpigmentation Complicationsmentioning

confidence: 99%

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Evaluating the Risk Factors of Post Inflammatory Hyperpigmentation Complications with Nd-YAG Laser Toning Using LASSO-Based Algorithm

et al. 2020

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The neodymium-doped yttrium aluminum garnet (Nd-YAG) laser is used for removal of pigmented skin patches and rejuvenation of skin. However, complications such as hyperpigmentation, hypopigmentation, and petechiae can occur after frequent treatments. Therefore, identifying the risk factors for such complications is important. The development of a multivariable logistic regression model with least absolute shrinkage and selection operator (LASSO) is needed to provide valid predictions about the incidence of post inflammatory hyperpigmentation complication probability (PIHCP) among patients treated with Nd-YAG laser toning. A total of 125 female patients undergoing laser toning therapy between January 2014 and January 2016 were examined for post-inflammatory hyperpigmentation (PIH) complications. Factor analysis was performed using 15 potential predictive risk factors of PIH determined by a physician. The LASSO algorithm with cross-validation was used to select the optimal number of predictive risk factors from the potential factors for a multivariate logistic regression PIH complication model. The optimal number of predictive risk factors for the model was five: immediate endpoints of laser (IEL), α-hydroxy acid (AHA) peels, Fitzpatrick skin phototype (FSPT), acne, and melasma. The area under the receiver operating characteristic curve (AUC) was 0.79 (95% CI, 0.70–0.88) in the optimal model. The overall performance of the LASSO-based PIHCP model was satisfactory based on the AUC, Omnibus, Nagelkerke R2, and Hosmer–Lemeshow tests. This predictive risk factor model is useful to further optimize laser toning treatment related to PIH. The LASSO-based PIHCP model could be useful for decision-making.

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“…Many other options that could also help to improve results are being more accepted nowadays, including oral tranexamic acid, antioxidants, and laser-assisted drug delivery [34] . Several studies have been conducted to find the best way to treat melasma.…”

Section: Picosecond Lasersmentioning

confidence: 99%

Energy-based devices for treatment of melasma

Jordão

Rebellato

2017

J Surg Dermatol

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Melasma, as a pigmentation disorder, induces significant stress to the patients and its recurrent nature remains a challenge in clinical practice. Treatment is based on a variety of mechanisms to prevent and/or stop the pigment production process by destroying the deposited pigment for removal or release, by peeling cells to improve their turnover, and by reducing inflammation. The use of appropriate devices and correct settings are crucial in the treatment of melasma. Cases unresponsive to topical bleaches or chemical peels should be referred for laser therapy. It is important that a maintenance therapy to avoid the recurrence of melasma be indicated. In this paper, we review energy-based devices for melasma treatment.

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A review of melasma treatment focusing on laser and light devices

Cited by 23 publications

References 0 publications

Dermoscopy as a useful tool for evaluating melasma and assessing the response to 1064‐nm Q‐switched Nd: YAG laser

Dermoscopy as a useful tool for evaluating melasma and assessing the response to 1064‐nm Q‐switched Nd: YAG laser

Evaluating the Risk Factors of Post Inflammatory Hyperpigmentation Complications with Nd-YAG Laser Toning Using LASSO-Based Algorithm

Energy-based devices for treatment of melasma

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