Patients with Small Abdominal Aortic Aneurysm are at Significant Risk of Cardiovascular Events and this Risk is not Addressed Sufficiently

Bath, Michael; Saratzis, Athanasios; Saedon, Mahmud; Sidloff, David; Sayers, Robert D.; Bown, Matthew J.; Pathak, Rahul; Brooks, Marcus; Hayes, Paul D.; Imray, Chris; Quarmby, John; Choksy, Sohail; Earnshaw, J. J.; Shearman, Cliff; Grocott, E.; Rix, Thomas Andersen; Chetter, Ian; Tennant, William G.; Libertiny, G.; Sykes, Timothy C.F.; Dayer, Maud-Laure; Pike, Luke; Pherwani, A.D.; Nice, Colin; Browning, Neil; McCollum, CN; Yusuf, Salim; Gannon, M. M.; Barwell, Julian; Baker, Sarah M.; Vallabhaneni, S. Rao; Davies, Allan

doi:10.1016/j.ejvs.2016.10.013

Cited by 40 publications

(33 citation statements)

References 21 publications

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“…This is similar to findings in animal models 54 and in people receiving treatment for systemic hypertension. 55,56 Another limitation of our study was a lack of histological correlation in these canine patients.…”

Section: F I G U R Ementioning

confidence: 95%

Aortic to caudal vena cava ratio measurements using abdominal ultrasound are increased in dogs with confirmed systemic hypertension

Holland

Hudson

Bao

et al. 2019

Vet Radiology Ultrasound

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Chronically sustained systemic hypertension in dogs can damage the kidneys, eye, brain, heart, and vessels. In human medicine, systemic hypertension has been implicated as the most common risk factor for aorta dilation, which can progress to an aneurysm. Abdominal ultrasound has been commonly used to monitor the size of the abdominal aorta in people with systemic hypertension. In this retrospective cross‐sectional abdominal ultrasound study, evaluation of the size of the abdominal aorta relative to the caudal vena cava was performed in 18 control dogs and 128 dogs with confirmed systemic hypertension. Preexisting conditions contributing to systemic hypertension in these dogs were renal disease, hyperadrenocorticism, diabetes mellitus, adrenal tumors, and previous administration of phenylpropanolamine or palladia. The abdominal aorta and caudal vena cava were assessed from longitudinal images cranial to the trifurcation with measurements made from outer border to outer border of the walls, being careful not to compress the caudal vena cava that would alter its size. Our hypothesis was the ratio of the diameter of the abdominal aorta to caudal vena cava would be higher in dogs with systemic hypertension compared to dogs with normal blood pressure. The mean abdominal aorta‐caudal vena cava ratio was 1.028 in control dogs with a normal blood pressure and 1.515 in dogs with systemic hypertension. In dogs with confirmed systemic hypertension, the abdominal aorta was dilated compared to the caudal vena cava in the caudal abdomen. An increase in the abdominal aorta‐caudal vena cava ratio in a dog should raise suspicion for the presence of systemic hypertension and prompt evaluation of blood pressure.

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Section: F I G U R Ementioning

confidence: 95%

Aortic to caudal vena cava ratio measurements using abdominal ultrasound are increased in dogs with confirmed systemic hypertension

Holland

Hudson

Bao

et al. 2019

Vet Radiology Ultrasound

View full text Add to dashboard Cite

show abstract

“…In the NHS AAA Screening Programme (NAAASP), there are currently almost 13,000 of these men who are offered regular surveillance and advice from a vascular nurse. Rupture rates are reassuringly low (<0.5%) in these men (unpublished data), but they are at risk of cardiovascular complications, 9 and their optimal management is unknown. It is suggested that men in surveillance who are taking antiplatelet and statin therapy have a lower risk of death from cardiovascular complications.…”

mentioning

confidence: 99%

Update on Screening for Abdominal Aortic Aneurysm

Earnshaw¹,

Lees²

2017

European Journal of Vascular and Endovascular Surgery

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“…Repairing small aneurysms (under 5.5 cm) has no known benefit [18]. However, early detection provides an opportunity for close monitoring and intervention (eg, smoking cessation) to reduce accelerated aneurysm growth and overall cardiovascular risk [19,20]. Nevertheless, guidelines on optimal AAA follow-up remain inconclusive, and follow-up rates are poor, often owing to referring provider failure to order repeat scans [21,22].…”

Section: Discussionmentioning

confidence: 99%

Abdominal Aortic Aneurysm Screening Practices: Impact of the 2014 U.S. Preventive Services Task Force Recommendations

Misono

Prabhakar

2017

Journal of the American College of Radiology

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Patients with Small Abdominal Aortic Aneurysm are at Significant Risk of Cardiovascular Events and this Risk is not Addressed Sufficiently

Cited by 40 publications

References 21 publications

Aortic to caudal vena cava ratio measurements using abdominal ultrasound are increased in dogs with confirmed systemic hypertension

Aortic to caudal vena cava ratio measurements using abdominal ultrasound are increased in dogs with confirmed systemic hypertension

Update on Screening for Abdominal Aortic Aneurysm

Abdominal Aortic Aneurysm Screening Practices: Impact of the 2014 U.S. Preventive Services Task Force Recommendations

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