Abstract:McIntosh, ND, Love, TD, Haszard, J, Osborne, H, and Black, KE. β-hydroxy β-methylbutyrate (HMB) supplementation effects on body mass and performance in elite male rugby union players. J Strength Cond Res 32(1): 19-26, 2018-Preseason is characterized by high training volumes with short recovery periods β-hydroxy β-methylbutyrate (HMB) has been postulated to assist with recovery. β-hydroxy β-methylbutyrate has been shown to improve strength and body composition among untrained groups; the benefits of HMB among t… Show more
“…A total of 208 subjects were included in the statistical analysis of HMB and BM from 7 different studies (8,9,17,19,25,35,44). A total of 161 subjects were included in the statistical analysis of HMB on FFM from 5 studies (8,17,25,35,44).…”
Section: Descriptive Resultsmentioning
confidence: 99%
“…A total of 161 subjects were included in the statistical analysis of HMB on FFM from 5 studies (8,17,25,35,44). A total of 128 subjects were included in the statistical analysis on FM from 5 studies (9,17,19,25,44). Subjects competed in various sports including indoor volleyball (25), American football (17), mixed martial arts (8), rowing (8,35), water polo (35), rugby union (19), canoe (9), and basketball (44).…”
Section: Descriptive Resultsmentioning
confidence: 99%
“…A total of 128 subjects were included in the statistical analysis on FM from 5 studies (9,17,19,25,44). Subjects competed in various sports including indoor volleyball (25), American football (17), mixed martial arts (8), rowing (8,35), water polo (35), rugby union (19), canoe (9), and basketball (44). Only the study by Slater et al (35) fits the criteria for resistance-trained individuals.…”
Section: Descriptive Resultsmentioning
confidence: 99%
“…Consistent with previous research on athletes, the analysis also demonstrated supplementation with HMB had no effect on BM (20.02 6 0.04; p 5 0.70) and a small, nonsignificant effect on FM (ES 5 20.33 6 0.23; p 5 0.22). The variability in outcome reporting led to different data being included in each analysis, with reporting differences for BM (8,9,17,19,25,35,44), FFM (8,17,25,35,44) and FM (9,17,19,25,44).…”
Section: Discussionmentioning
confidence: 99%
“…Research has demonstrated HMB increases muscle protein synthesis (;70%) (40,41), decreases muscle protein breakdown (;57%) (40,41), and improves muscle membrane stability (;25%) (4). However, results from human trials supplemented with HMB are equivocal, with some studies suggesting a benefit (8,9,13,16,18,19,25), while others showing none (12,17,24,27,28,31,35). Owing to the variability in the results of HMB studies, this meta-analysis sought to clarify the effects of HMB on body composition in athletes, a population that would seemingly benefit from the supplement given their rigorous training practices.…”
Holland, BM, Roberts, BM, Krieger, JW, and Schoenfeld, BJ. Does HMB enhance body composition in athletes? A systematic review and meta-analysis. J Strength Cond Res 36(2): 585-592, 2022-The purpose of this article was to systematically review and meta-analyze the current literature to determine the effects of HMB on body composition in athletes. Studies were deemed eligible for inclusion if they met the following criteria: (a) were an experimental design published in a peer-reviewed, English-language journal; (b) included human athletic populations; (c) assessed body mass (BM), fat mass (FM), or fat-free mass (FFM) using a validated measure; (d) and had a minimum supplementation period of 4 weeks. Separate analyses were performed for BM, FM, and FFM using robust variance random-effects meta-regression for multilevel data structures, with adjustments for small samples. The final analysis of BM comprised a total of 208 subjects from 7 studies. Analysis of FFM and FM encompassed 5 studies comprising 161 subjects and 5 studies comprising 128 subjects, respectively. The principal finding of this analysis suggests HMB may have a small, positive impact on FFM in athletes (0.30 6 0.13; 95% confidence interval [CI]: 20.07 to 0.68; p 5 0.08), although this seems specific to when protein intake is suboptimal (,1.6 g•kg 21 •d 21 ). Consistent with previous research on athletes, HMB demonstrated no significant effect on BM (20.02 6 0.04; 95% CI: 20.14 to 0.10; p 5 0.70) and a small, nonsignificant effect on FM (20.33 6 0.23; 95% CI: 20.96 to 0.31; p 5 0.22). More research is required to establish HMB's influence on FFM in athletes. It is also important to consider the dosage of HMB and training parameters of athletes because these will likely influence the efficacy of supplementation.
“…A total of 208 subjects were included in the statistical analysis of HMB and BM from 7 different studies (8,9,17,19,25,35,44). A total of 161 subjects were included in the statistical analysis of HMB on FFM from 5 studies (8,17,25,35,44).…”
Section: Descriptive Resultsmentioning
confidence: 99%
“…A total of 161 subjects were included in the statistical analysis of HMB on FFM from 5 studies (8,17,25,35,44). A total of 128 subjects were included in the statistical analysis on FM from 5 studies (9,17,19,25,44). Subjects competed in various sports including indoor volleyball (25), American football (17), mixed martial arts (8), rowing (8,35), water polo (35), rugby union (19), canoe (9), and basketball (44).…”
Section: Descriptive Resultsmentioning
confidence: 99%
“…A total of 128 subjects were included in the statistical analysis on FM from 5 studies (9,17,19,25,44). Subjects competed in various sports including indoor volleyball (25), American football (17), mixed martial arts (8), rowing (8,35), water polo (35), rugby union (19), canoe (9), and basketball (44). Only the study by Slater et al (35) fits the criteria for resistance-trained individuals.…”
Section: Descriptive Resultsmentioning
confidence: 99%
“…Consistent with previous research on athletes, the analysis also demonstrated supplementation with HMB had no effect on BM (20.02 6 0.04; p 5 0.70) and a small, nonsignificant effect on FM (ES 5 20.33 6 0.23; p 5 0.22). The variability in outcome reporting led to different data being included in each analysis, with reporting differences for BM (8,9,17,19,25,35,44), FFM (8,17,25,35,44) and FM (9,17,19,25,44).…”
Section: Discussionmentioning
confidence: 99%
“…Research has demonstrated HMB increases muscle protein synthesis (;70%) (40,41), decreases muscle protein breakdown (;57%) (40,41), and improves muscle membrane stability (;25%) (4). However, results from human trials supplemented with HMB are equivocal, with some studies suggesting a benefit (8,9,13,16,18,19,25), while others showing none (12,17,24,27,28,31,35). Owing to the variability in the results of HMB studies, this meta-analysis sought to clarify the effects of HMB on body composition in athletes, a population that would seemingly benefit from the supplement given their rigorous training practices.…”
Holland, BM, Roberts, BM, Krieger, JW, and Schoenfeld, BJ. Does HMB enhance body composition in athletes? A systematic review and meta-analysis. J Strength Cond Res 36(2): 585-592, 2022-The purpose of this article was to systematically review and meta-analyze the current literature to determine the effects of HMB on body composition in athletes. Studies were deemed eligible for inclusion if they met the following criteria: (a) were an experimental design published in a peer-reviewed, English-language journal; (b) included human athletic populations; (c) assessed body mass (BM), fat mass (FM), or fat-free mass (FFM) using a validated measure; (d) and had a minimum supplementation period of 4 weeks. Separate analyses were performed for BM, FM, and FFM using robust variance random-effects meta-regression for multilevel data structures, with adjustments for small samples. The final analysis of BM comprised a total of 208 subjects from 7 studies. Analysis of FFM and FM encompassed 5 studies comprising 161 subjects and 5 studies comprising 128 subjects, respectively. The principal finding of this analysis suggests HMB may have a small, positive impact on FFM in athletes (0.30 6 0.13; 95% confidence interval [CI]: 20.07 to 0.68; p 5 0.08), although this seems specific to when protein intake is suboptimal (,1.6 g•kg 21 •d 21 ). Consistent with previous research on athletes, HMB demonstrated no significant effect on BM (20.02 6 0.04; 95% CI: 20.14 to 0.10; p 5 0.70) and a small, nonsignificant effect on FM (20.33 6 0.23; 95% CI: 20.96 to 0.31; p 5 0.22). More research is required to establish HMB's influence on FFM in athletes. It is also important to consider the dosage of HMB and training parameters of athletes because these will likely influence the efficacy of supplementation.
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