278: Impact of pre-pregnancy body mass index on maternal and fetal outcomes in type 1 diabetitc preganancy (T1DM)

Patanè, Luisa; Pirola, Serena; Barresi, Santa; Cavalli, Giorgia; Strobelt, Nicola; Frigerio, Luigi; Dodesini, Alessandro Roberto; Trevisan, Roberto; Ciriello, Elena

doi:10.1016/j.ajog.2012.10.443

Cited by 1 publication

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“…Identification followed by the quantification of the level of blood glucose is mandatory during the period of pregnancy [24, 25]. A higher level of glucose is causing various health issues to the mother and foetus during and after the pregnancy period and generates the complications.…”

Section: Resultsmentioning

confidence: 99%

Gold Nanorod Integrated Electrochemical Sensing for Hyperglycaemia on Interdigitated Electrode

Zheng

Zhang

Lakshmipriya

et al. 2019

BioMed Research International

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Gestational diabetes (hyperglycaemia) is an elevated blood sugar level diagnosed during the period of pregnancy and affects the baby’s health. Hyperglycaemia has been found within the gestational weeks between 24 and 28, and the foetus has also the possibility of getting out prior to this test frame; it causes excessive birth weight, early birth, low-blood sugar level, respiratory distress syndrome, and type-2 diabetes to the mother. It creates a mandatory situation to identify the hyperglycaemia at least during the pregnancy weeks from 18 to 20. Further, a continuous monitoring of the level of glucose is necessary for the proper delivery. In this work, a method is introduced for glucose detection at 0.06 mg/mL, assisted by gold nanorod (GNR)-conjugated glucose oxidase (GOx) on interdigitated electrode sensor. In the absence of GNR, GOx shows the limit of glucose detection to be 0.25 mg/mL. Moreover, with GOx-GNR the reactions of all the glucose concentrations have recorded higher levels of the current from the baseline. With the specificity analysis, it was found that the glucose only reacts with GOx-GNR and discriminates other sugars efficiently. This method of detection is useful to diagnose and continuously monitor the glucose level during the pregnancy period.

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Section: Resultsmentioning

confidence: 99%