Diagnosis of nail psoriasis: evaluation of nail-derived microRNAs as potential novel biomarkers

Wang, Zhongzhi; Jinnin, Masatoshi; Harada, Masaki; Kudo, Hideo; Inoue, Kuniko; Nakayama, Wakana; Honda, Noritoshi; Makino, Katsunari; Kajihara, Ikko; Fukushima, Satoshi; Ihn, Hironobu

doi:10.1684/ejd.2016.2906

Cited by 6 publications

(2 citation statements)

References 24 publications

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“…miR-146a may regulate the expression of VEGF through the target gene Smad4 at the translation level, and the overexpression of VEGF promotes the inflammatory response and angiogenesis of psoriasis, and promotes the occurrence and development of psoriasis [14]. In recent years, serum miRNA levels have been found to be useful biomarkers in the diagnosis, prevention and treatment of various diseases [15] [16].…”

Section: Discussionmentioning

confidence: 99%

Expression of miR-155 and miR-146a in Skin Tissue, Peripheral Blood Mononuclear Cells and Serum of Patients with Psoriasis and Its Clinical Significance

Gu¹,

Cheng²,

Feng³

2022

ABB

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Section: Discussionmentioning

confidence: 99%

Expression of miR-155 and miR-146a in Skin Tissue, Peripheral Blood Mononuclear Cells and Serum of Patients with Psoriasis and Its Clinical Significance

Gu¹,

Cheng²,

Feng³

2022

ABB

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“…There are other body fluids where miRNAs have been detected and associated with certain cancers or disorders– saliva ( 104 – 106 ), sweat ( 107 ), tear ( 108 – 111 ), and stool ( 112 , 113 ). Besides, fingernails are also found to be a promising sample for the detection of miRNAs ( 114 ). Importantly, the characteristics such as the area under curve (AUC), sensitivity, and specificity should be considered while selecting the most suitable biomarker for BC diagnosis.…”

Section: Diagnostic and Prognostic Function Of Mirnas In Breast Cancermentioning

confidence: 99%

Potential utility of miRNAs for liquid biopsy in breast cancer

et al. 2022

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Breast cancer (BC) remains the most prevalent malignancy due to its incidence rate, recurrence, and metastasis in women. Conventional strategies of cancer detection– mammography and tissue biopsy lack the capacity to detect the complete cancer genomic landscape. Besides, they often give false- positive or negative results. The presence of this and other disadvantages such as invasiveness, high-cost, and side effects necessitates developing new strategies to overcome the BC burden. Liquid biopsy (LB) has been brought to the fore owing to its early detection, screening, prognosis, simplicity of the technique, and efficient monitoring. Remarkably, microRNAs (miRNAs)– gene expression regulators seem to play a major role as biomarkers detected in the samples of LB. Particularly, miR-21 and miR-155 among other possible candidates seem to serve as favorable biomarkers in the diagnosis and prognosis of BC. Hence, this review will assess the potential utility of miRNAs as biomarkers and will highlight certain promising candidates for the LB approach in the diagnosis and management of BC that may optimize the patient outcome.

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Latest Research in Nail Psoriasis

Pasch

Iorizzo

2021

Advances in Nail Disease and Management

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Diagnosis of nail psoriasis: evaluation of nail-derived microRNAs as potential novel biomarkers

Cited by 6 publications

References 24 publications

Expression of miR-155 and miR-146a in Skin Tissue, Peripheral Blood Mononuclear Cells and Serum of Patients with Psoriasis and Its Clinical Significance

Expression of miR-155 and miR-146a in Skin Tissue, Peripheral Blood Mononuclear Cells and Serum of Patients with Psoriasis and Its Clinical Significance

Potential utility of miRNAs for liquid biopsy in breast cancer

Latest Research in Nail Psoriasis

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