The analysis of scalp irritation by coacervates produced in hair shampoo via FTIR with focal plane array detector, X‐ray photoelectron microscopy and HaCaT cells

Jung, In Keun; Park, S. C.; Kim, S. H.; Kim, J. H.; R, Nalaeram Sivaram; Bae, Woo-Ri; Kim, H. N.; Cho, S. A.; Yoo, Jae Won; Kim, B. M.; Lee, J. H.

doi:10.1111/ics.12360

Cited by 5 publications

(6 citation statements)

References 13 publications

(3 reference statements)

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“…A disruption of the composition of the microbiome due to a change in scalp temperature often leads to detrimental scalp conditions by inducing dandruff. Thus, a change in scalp temperature can be a deciding factor of a healthy scalp …”

Section: Resultsmentioning

confidence: 99%

“…People with sensitive scalps must pay greater attention to scalp health than those with non‐sensitive scalps, and using mild and low‐anionic surfactant products is recommended. Coacervates created with some scalp products cause irritation when they interact with water as a result of their particle structure; if they remain as a residue on the hair follicle or pores and then expand with water, this can help contaminants to penetrate and induce irritation …”

Section: Introductionmentioning

confidence: 99%

“…For this reason, a change of scalp temperature, or heat sensation, can form the basis of dividing sensitive/non‐sensitive scalp criteria. Therefore, it is necessary to consider the scalp temperature when examining the factors associated with triggering a sensitive scalp …”

Section: Introductionmentioning

confidence: 99%

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Evaluation of factors triggering sensitive scalp in Korean adult women

Park¹,

Kim²,

Oh³

et al. 2019

Skin Res Technol

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Background The scalp care market is growing rapidly and research into the factors associated with sensitive scalp is performed in many countries. However, to the best of our knowledge, no previous study has examined the factors triggering sensitive scalp in Korean women. Thus, the aim of our study was to establish objective standards for sensitive scalp, investigate factors that trigger this condition, and determine the ratio of sensitive scalp in Korean women. Methods A total of 125 Korean adult women participated in the study. The participants answered the questionnaire, had their scalp temperature measured, and the sensitive scalp condition was evaluated and analyzed. Results Compared to the non‐sensitive scalp (NS) group, the sensitive scalp (SS) group had a significantly higher average temperature and increased heat sensation, dandruff, erythema in the scalp, past history of atopy, history of hair loss, medical history of scalp disease, concern for scalp care, and interest in mild products and frequency of use. The majority of participants in the SS group had a dry scalp, and itching was common. Conclusion This study may help us to understand the characteristics of the sensitive scalp in Korean females and determine factors associated with triggering a sensitive scalp.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Evaluation of factors triggering sensitive scalp in Korean adult women

Park¹,

Kim²,

Oh³

et al. 2019

Skin Res Technol

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“…The two advantages of the FPA detector are that any material remaining on a hair surface or detected inside the hair fibre through cross‐sectioning can be easily identified in a non‐destructive way, and sample preparation is not necessary. It has been previously shown that FTIR‐FPA can be used to show that materials are deposited on the scalp from a shampoo that can form coacervates . It has also been shown using FTIR‐FPA that amino acids and xylose can undergo the Maillard reaction inside hair fibres .…”

Section: Discussionmentioning

confidence: 99%

Development of a stiffness‐angle law for simplifying the measurement of human hair stiffness

Jung

Park

Lee

et al. 2018

Intern J of Cosmetic Sci

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“…In this study, we have used MD simulations to identify the differences between the lipid layer with reduced ceramide content, as seen in atopic conditions, and the lipid layer of normal skin. Further, we aimed to examine the skin barrier function of the atopic lipid layer by calculating the potential mean force (PMF) between sodium laureth sulfate (SLES), a well‐studied skin irritant, and the lipid layer 18 …”

Section: Introductionmentioning

confidence: 99%

Modeling lipid layers of atopic skin and observation of changes in lipid layer properties with changes in ceramide content

Jung

Choi

Nam

et al. 2020

J of Cosmetic Dermatology

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Background Studies have shown that there is a high correlation between atopic dermatitis and decrease in ceramide content in the lipid bilayer of skin. Moreover, it has been shown that the reduction in ceramide content in the stratum corneum is unique to atopic dermatitis, indicating that there are particular structural differences between the lipid bilayers of normal and atopic skin. Aim This study aimed to compare the lipid bilayer of the atopic skin with that of the healthy skin and to establish a structural model of the lipid bilayer for atopy. Methods Molecular dynamics simulations were performed using NAMD 2.8. Models of lipid bilayers of normal skin and atopic skin, and a model of lipid bilayer containing only ceramide were built with CHARMM‐GUI. The thickness, area occupied per lipid, and alignment of lipids were compared among the three models. Potential mean force (PMF) of the sodium laureth sulfate (SLES) on lipid bilayers was calculated to predict the affinity between SLES and lipid bilayers. Results Potential mean force calculations showed that the lipid bilayer of atopic skin was able to absorb the surfactant more easily than that of normal skin. Conclusions When the ceramide ratio is low, the thickness of lipid bilayer is reduced and its structure is weakened. Other structural differences between the lipid layers of normal and atopic skin included increased area per lipid and poor alignment of lipids. Further, the atopy lipid bilayer model was found to absorb more SLES than the normal skin lipid bilayer model.

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The analysis of scalp irritation by coacervates produced in hair shampoo via FTIR with focal plane array detector, X‐ray photoelectron microscopy and HaCaT cells

Abstract: Coacervate releases sulphate bonding into the matrix when it is exposed to water. Thus, the scalp stimulation would be expected.

Cited by 5 publications

References 13 publications

Evaluation of factors triggering sensitive scalp in Korean adult women

Evaluation of factors triggering sensitive scalp in Korean adult women

Development of a stiffness‐angle law for simplifying the measurement of human hair stiffness

Modeling lipid layers of atopic skin and observation of changes in lipid layer properties with changes in ceramide content

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