Uncontrolled Hypertension and Risk of Cardiovascular Mortality in China

Zhou, Donghao; Wang, Shiming; Tian, Tao

doi:10.1001/jamainternmed.2016.3819

Cited by 2 publications

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“…Among them, hypertension has been identified to be the second largest risk factor causing disability and death in China and the third leading risk factor of the total burden of diseases [ 5 , 6 ]. This is convinced in the studies from China during the last thirty years which have reported an increasing prevalence of hypertension [ 7 – 9 ]. A cohort study from China showed that one third Chinese adults had hypertension and the prevalence increased with age (from 12.6% at 35–39 years of age to 58.4% at 70–74 years of age) [ 7 ].…”

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confidence: 90%

Blood pressure and noncommunicable diseases in middle-aged and older adults in China

et al. 2018

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BackgroundThere are few studies examining the association between blood pressure (BP) and noncommunicable diseases (NCDs) in consideration of the new hypertension guidelines in China.MethodsData were drawn from the China Health and Retirement Longitudinal Study. 14 390 eligible participants (aged 45 years and older) were selected through four-stage, stratified, and cluster sampling. Hypertension was considered as a mean systolic blood pressure (SBP) of 130 mm Hg (old definition: 140 mm Hg) or higher, a mean diastolic blood pressure (DBP) of 80 mm Hg (old definition: 90 mm Hg) or higher or taking anti-hypertensive medication. Cochran-Armitage trend test and logistic regression analyses were conducted to test the association between BP level and NCDs.ResultsThe prevalence of hypertension based on the latest definition was 56.35% (while by old definition: 42.75%). The awareness, treatment, and control among hypertensive participants were 38.62% (51.18%), 43.10% (56.81%), and 9.91% (13.06%), respectively. An increasing rate of NCDs (diabetes, heart disease, stroke, and memory-related disease) among participants were found with the ascending of BP level. After adjusted for demographics and behavioral risks, the following 3 NCDs had been shown to correlate with hypertension: diabetes (adjusted OR 1.15, 0.91–1.45 for elevated BP; 1.20, 0.97–1.49 for hypertension stage 1; 1.55, 1.28–1.86 hypertension stage 2), heart disease (0.94, 0.79–1.12; 1.05, 0.90–1.22; 1.28, 1.12–1.47), and stroke (1.77, 1.25–2.51; 1.32, 0.93–1.87; 1.85, 1.37–2.49).ConclusionsThe association between hypertension and the risk of NCDs is of concern in China. The combined efforts on NCDs prevention and lowered blood pressure should be made by nationally integrated strategies, especially in middle-aged and older adults.

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Section: Introductionmentioning

confidence: 90%

Blood pressure and noncommunicable diseases in middle-aged and older adults in China

et al. 2018

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The Impact of Uncontrolled Hypertension on the Longitudinal Systolic Function of the Left Ventricle

Bendiab

Benkhedda

Henaoui

et al. 2022

CHYR

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Background: The assessment of the longitudinal component of left ventricular (LV) function is of major clinical importance for the early detection of LV contractile impairment. The aim of this study was to determine the impact of uncontrolled hypertension, on LV longitudinal systolic performance. Methods: The study population included 400 hypertensive patients: 271 patients with uncontrolled blood pressure (BP) and 112 without controlled BP, all patients underwent a complete ultrasound evaluation with calculation of the LV mass, evaluation of diastolic function as well as longitudinal systolic function. Results: Conventional echo demonstrated that uncontrolled patients had increased LV mass (P 0.007), LA (left auricular) dimension (P 0.004), left ventricular wall thickness and impairment of diastolic function (E/E’6 ± 2.1 vs 7.4 ±3.0 P=0.001) while no affection of systolic function could be detected. By deformation imaging, there was a reduction in longitudinal strain (apical 4 view -16.2 ±2.9 vs -18.2± 2.6 P 0.02, apical 3 view -17.3 ± 3.3 vs. -18.9 ± 4.1 P 0.01). Similarly systolic strain rate (SRsys) and early diastolic SR (SRe) reduced significantly in longitudinal direction. Conclusion: Although EF was not different between uncontrolled patients and controls, LV longitudinal strain and strain rate by 2D speckle tracking were lower in the uncontrolled group.

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Uncontrolled Hypertension and Risk of Cardiovascular Mortality in China

Cited by 2 publications

References 1 publication

Blood pressure and noncommunicable diseases in middle-aged and older adults in China

Blood pressure and noncommunicable diseases in middle-aged and older adults in China

The Impact of Uncontrolled Hypertension on the Longitudinal Systolic Function of the Left Ventricle

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