“…Exercise training is a well-established non-pharmacological approach for patients with cardiovascular diseases (Nieuwland et al, 2000;Naci & Ioannidis, 2015). Several mechanisms have been proposed to explain the benefits promoted by exercise among these patients, including improvements in peripheral vascular function, peak oxygen uptake (VO 2peak ), muscle function, exercise tolerance, and reduction in body mass (Wisloff et al, 2007;Borges & Lessa, 2015;Borges et al, 2016b). However, few studies have investigated the influence of exercise training on microcirculatory impairments observed in CAD (Olsen et al, 2015).…”