Cutaneous Heterotopic Brain Tissue (Neuroglial Choristoma) with Dysplastic Features in a Kitten

Dorsal duplication of paw pads in the four limbs of a cat

“…Ocular dermoids are the most commonly reported choristomas as they represent well-differentiated tissue in an abnormal location. 4 Heterotopic neural tissue was found in the pharynx of a seven-week-old kitten, and a neuroglial cutaneous choristoma has been described in a kitten 2,5 ; however, to the best of the authors' knowledge, there are no previous reports of ectopic or heterotopic paw pads in cats. This report describes a unique case of dorsal duplication of all digital and metacarpal/metatarsal pads in a cat.…”

“…The term choristoma refers to normal tissue found in an abnormal location and may be used synonymously with the term heterotopia or ectopic tissue. 1,2 Choristomas and hamartomas are included within benign non-neoplastic lesions composed of mature tissues; however, while hamartomas are disorganised overgrowths resembling the tissues of their origin/location, choristomas consist of normal structured tissue in an abnormal site. 3 Developmental malformations such as choristomas or heterotopias and hamartomas are described rarely in the cat.…”

Ovarian Neuroglial Choristoma in a Bitch

“…Mature brain tissue at a site isolated from the cranium or spinal cord is termed neuroglial choristoma [1]. Decade after decade, this entity was improperly defined with various terms such as: "heterotopic brain tissue", "glioma", or "teratoma" [2][3][4][5], reflecting the controversy that exists regarding its pathogenesis [6][7][8]. In human medicine, neuroglial choristomas are considered malformations, with heterotopic neural tissue predominantly reported in the head and the neck [9].…”

“…In human medicine, neuroglial choristomas are considered malformations, with heterotopic neural tissue predominantly reported in the head and the neck [9]. In domestic animals, neuroglial choristomas are sporadic lesions reported only in the retina of a dog [10] and in the pharynx and the skin of two kittens [8,11]. In wildlife species, a perioral and oropharyngeal presentation was described in a neonatal harbor seal [7].…”