Extended-Spectrum Cephalosporin-Resistant<i>Salmonella enterica</i>serovar Heidelberg Strains, the Netherlands1

Liakopoulos, Apostolos; Geurts, Yvon; Dierikx, Cindy; Brouwer, Michael S. M.; Kant, A.; Wit, Ben; Heymans, Raymond; Pelt, Wilfrid van; Mevius, Dik

doi:10.3201/eid2207.151377

Cited by 55 publications

(68 citation statements)

References 13 publications

(11 reference statements)

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“…The most frequently-isolated bla CMY−2 carrying plasmids of S. Heidelberg isolates include IncI1 (e.g. subtyping ST12 and ST25) and IncA/C (ST2), which have likely contributed to the widespread distribution of CSH and other 3GC-resistant NTS serovars from human and animal sources [58, 83–85]. …”

Section: Results (Headings As Per the Codex Guidelines)mentioning

confidence: 99%

Ceftiofur-resistant Salmonella enterica serovar Heidelberg of poultry origin – a risk profile using the Codex framework

Carson

Agunos

et al. 2019

Epidemiol. Infect.

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Codex published the ‘Guidelines for Risk Analysis of Foodborne Antimicrobial Resistance’ to standardise the approach for evaluating risk posed by foodborne antimicrobial-resistant bacteria. One of the first steps in the guidelines is to compile a risk profile, which provides the current state of knowledge regarding a food safety issue, describes risk management options and recommends next steps. In Canada, ceftiofur/ceftriaxone-resistant Salmonella enterica subsp. enterica serovar Heidelberg from poultry was identified as an antimicrobial resistance (AMR) food safety issue. The first objective of this article was to contextualise this food safety issue, using the risk profile format of the Codex Guidelines. A second objective was to evaluate the applicability of the Codex Guidelines. This risk profile indicated that ceftiofur/ceftriaxone-resistant S. Heidelberg (CSH) was commonly isolated from poultry and was associated with severe disease in humans. Ceftiofur use in poultry hatcheries temporally mirrored the prevalence of CSH from poultry meat at retail and from people with salmonellosis. The evidence was sufficient to indicate the need for risk management options, such as restricting the use of ceftiofur in poultry. The Codex Guidelines provided a useful approach to summarise data for decision-makers to evaluate an AMR food safety issue.

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Section: Results (Headings As Per the Codex Guidelines)mentioning

confidence: 99%

Ceftiofur-resistant Salmonella enterica serovar Heidelberg of poultry origin – a risk profile using the Codex framework

Carson

Agunos

et al. 2019

Epidemiol. Infect.

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“…Quinolones were used frequently in treatment regimens and also as a feed additives in poultry industry [24] . In recent years several studies have been reported about third-generation cephalosporin resistance patterns of Salmonella was isolated from domestic animals and human [25][26][27] . In parallel with this situation, Kameyama et al emphasized that 3rd-generation cephalosporin-resistant S. Infantis associated with β-lactamases is increasing in worldwide [28] .…”

Section: Discussionmentioning

confidence: 99%

Class 1 Integrons and the Antibiotic Resistance Profile of Salmonella Infantis Strains from Broiler Chickens

Kaya¹,

Yapıcıer²,

Akan³

et al. 2017

Kafkas Univ Vet Fak Derg

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Citation of This ArticleKaya İB, Şahan Yapıcıer Ö, Akan M, Diker KS: Class 1 integrons and the antibiotic resistance profile of Salmonella infantis strains from broiler chickens. Kafkas Univ Vet Fak Derg, 23 (5): 803-807, 2017803-807, . DOI: 10.9775/kvfd.2017 Abstract Salmonella infections are one of the most important diseases and cause economic problems in poultry. The zoonotic feature of the agent and leading to food-borne infections are also important in public health issues. Increasing antibiotic resistance causes difficulties of controlling Salmonella infections, in recent years. Among non-typhoidal Salmonella serotypes the rate of Salmonella Infantis are increasing in Turkey. With this increase, it is important to know the antimicrobial resistance patterns of Salmonella Infantis strains as seen in other Salmonella serotypes. In this study, we aimed to investigate Salmonella Infantis strains which were isolated from feces of healthy broiler chickens for the presence of antibiotic resistance and frequency of Class 1 integrons that is responsible for the transfer of antibiotic resistance as plasmids, transposons. For this purpose a total of 150 S. Infantis strains which were isolated and identified according to the ISO 6579-2002 and Kauffmann-White serotyping scheme were used. Antimicrobial resistance of the strains was determined by the disc diffusion method following to the recommendations of CLSI 2011 standard protocol and also Class 1 integrons were investigated by PCR. According to the results, high rate of multi-drug antibiotic resistance (89.3%), high rate of sensitivity (100%) to cefotaxime, ciprofloxacin, gentamicin, ceftazidime were observed and also Class 1 integrons were determined in all isolates. In conclusion, the presence of Class 1 integron is all strains of Salmonella Infantis showed the potential importance of these strains as recipient for antibiotic resistance.

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“…Presumptive extended-spectrum-cephalosporinase-producing isolates were identified using matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometry (Brucker, Coventry, United Kingdom), while Salmonella isolates were further serotyped by the microtitration method. Antibiotic susceptibility of the isolates was assessed by broth microdilution and interpreted according the epidemiologic cutoff values recommended by the European Committee on Antimicrobial Susceptibility Testing (http://mic .eucast.org), whereas ESBL and/or AmpC production was evaluated by a combined disc test, as previously described (9).…”

mentioning

confidence: 99%

“…Genes conferring the ESC r phenotype were sought and their genetic location on either the chromosome or a plasmid was determined as previously described (9). Standard methods (PCRbased replicon [rep] typing, plasmid multilocus sequence typing [pMLST]/plasmid double-locus sequence typing [pDLST]/replicon sequence typing [RST], and S1 nuclease pulsed-field gel electrophoresis [PFGE]) were applied for further plasmid analysis, while the conjugal transferability of the extended-spectrum cephalosporinase genes and the presence of known insertion sequences (ISs) upstream of them were examined (9).…”

mentioning

confidence: 99%

“…Standard methods (PCRbased replicon [rep] typing, plasmid multilocus sequence typing [pMLST]/plasmid double-locus sequence typing [pDLST]/replicon sequence typing [RST], and S1 nuclease pulsed-field gel electrophoresis [PFGE]) were applied for further plasmid analysis, while the conjugal transferability of the extended-spectrum cephalosporinase genes and the presence of known insertion sequences (ISs) upstream of them were examined (9). Genetic relatedness among Escherichia coli and Salmonella enterica serotype Heidelberg isolates was assessed by MLST and XbaI-PFGE typing, respectively, as previously described (9,10).…”

mentioning

confidence: 99%

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Molecular Characterization of Extended-Spectrum-Cephalosporin-Resistant Enterobacteriaceae from Wild Kelp Gulls in South America

Liakopoulos

Olsén

Geurts

et al. 2016

Antimicrob Agents Chemother

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Extended-spectrum-cephalosporin-resistant Enterobacteriaceae are a public health concern due to limited treatment options. Here, we report on the occurrence and the molecular characteristics of extended-spectrum-cephalosporin-resistant Enterobacteriaceae recovered from wild birds (kelp gulls). Our results revealed kelp gulls as a reservoir of various extended-spectrum cephalosporinase genes associated with different genetic platforms. In addition, we report for the first time the presence of a known epidemic clone of Salmonella enterica serotype Heidelberg (JF6X01.0326/XbaI.1966) among wild birds.

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Extended-Spectrum Cephalosporin-ResistantSalmonella entericaserovar Heidelberg Strains, the Netherlands1

Cited by 55 publications

References 13 publications

Ceftiofur-resistant Salmonella enterica serovar Heidelberg of poultry origin – a risk profile using the Codex framework

Ceftiofur-resistant Salmonella enterica serovar Heidelberg of poultry origin – a risk profile using the Codex framework

Class 1 Integrons and the Antibiotic Resistance Profile of Salmonella Infantis Strains from Broiler Chickens

Molecular Characterization of Extended-Spectrum-Cephalosporin-Resistant Enterobacteriaceae from Wild Kelp Gulls in South America

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