2016
DOI: 10.1021/acs.inorgchem.6b01013
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Graphitic Carbon Nanocubes Derived from ZIF-8 for Photothermal Therapy

Abstract: Graphitic carbon nanocubes (GCNCs) were prepared by pyrolysis of ZIF-8 nanocubes. The GCNCs resemble the structure of N-doped graphite and exhibit a high photothermal conversion efficiency of 40.4%. In vitro tests demonstrate that the GCNCs are highly biocompatible and induce an effective photothermal therapy effect under 808 nm irradiation. Our study provides a facile strategy for preparing functional carbon nanomaterials of prescribed size, morphology, and porous structure for bioapplications.

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Cited by 21 publications
(7 citation statements)
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“…From Figure S3A, it is clear that the four elements (C, N, O, and Zn) exist in the sample, which is in agreement with the EDS results (Figure D). From Figure B, the C 1s spectrum of the NPC-ZnO nanopolyhedra can be deconvoluted into three peaks at 284.7, 285.3, and 288.1 eV, which are associated with C sp 3 –C sp 3 , C sp 2 –C sp 2 , and CN, respectively . Similarly, the N 1s spectrum of the NPC-ZnO nanopolyhedra can be mainly deconvoluted into two peaks centered at about 398.5 and 400.2 eV, which are assignable to pyridinic N and pyrrolic N, respectively (Figure C) .…”
Section: Resultsmentioning
confidence: 94%
“…From Figure S3A, it is clear that the four elements (C, N, O, and Zn) exist in the sample, which is in agreement with the EDS results (Figure D). From Figure B, the C 1s spectrum of the NPC-ZnO nanopolyhedra can be deconvoluted into three peaks at 284.7, 285.3, and 288.1 eV, which are associated with C sp 3 –C sp 3 , C sp 2 –C sp 2 , and CN, respectively . Similarly, the N 1s spectrum of the NPC-ZnO nanopolyhedra can be mainly deconvoluted into two peaks centered at about 398.5 and 400.2 eV, which are assignable to pyridinic N and pyrrolic N, respectively (Figure C) .…”
Section: Resultsmentioning
confidence: 94%
“…The therapeutic efficacy of PTT normally relies on the conversion of light to adequate heat via nanoscale photothermal agents. To date, a variety of nanotherapeutics such as gold nanoparticles (NPs), metal sulfides, nanocarbons, and organic nanoagents have been widely studied. Unremarkably, the use of nanoparticles (NPs) as PTT agents has attracted particular attention because of the easy availability of their precursors, their simple preparation strategies and easy functionalization, their large absorption range in NIR, their solubility in biocompatible solvents, and their high photothermal conversion efficiencies. …”
Section: Introductionmentioning
confidence: 99%
“…Figure S1B shows the high-resolution XPS of C 1s. The peak at 282.6 eV is attributed to the binding energy of the C sp 3 orbital . The NPC–ZnO nanopolyhedron has a peak at 396.5 eV in the N 1s spectrum (Figure S1C), which is attributed to pyridine nitrogen .…”
Section: Resultsmentioning
confidence: 99%
“…The peak at 282.6 eV is attributed to the binding energy of the C sp 3 orbital. 26 The NPC−ZnO nanopolyhedron has a peak at 396.5 eV in the N 1s spectrum (Figure S1C), which is attributed to pyridine nitrogen. 27 The presence of lone electron pairs promotes electron transfer, providing additional advantages for PEC biosensors.…”
Section: ■ Results and Discussionmentioning
confidence: 99%