Herpes Zoster-Related Health Care Resource Utilization in Cancer Patients in 5 European Countries

Abstract

for influenza vaccination, ILI symptoms, time off work/education, and HCRU. Transmission of ILI from children to adults was estimated. Descriptive statistics were used. Results: Across 938 participants/households there were 1895 adults mean age 40.6 years, 52.7% females; 1695 children mean age 8.7 years, 46.8% females. 91/306 adult ILI incidences were related to a child ILI (29.7%, 95%CI:26.5%-33.0%). 69 of these (75.8%, 95%CI:60.3%-91.3%) had symptom duration> 3 days, 31/86 employed (36.0%; 95%CI:28.5%-43.6%) reported taking time off work with 22/31 (71.0%; 95%CI:46.2%-95.8%) taking ≥ 2 days off. 13/91 (14.3%; 95%CI:11.5%-17.1%) had general practice (GP) visits, 5/91 (5.5%; 95%CI:4.5%-6.5%) had GP telephone consultations, 6/91 (6.6%; 95%CI:5.3%-7.8%) received prescriptions, 76/91 (83.5%; 95%CI:66.5-100.6%) used over the counter (OTC) medications because of their ILI. 67 adults reported time off because of child ILIs (310 incidences); 30/67 (44.8%; 95%CI:34.2%-55.4%) taking ≥ 2 days. This represents 67 adults/152 working adults (44.1%; 95%CI:37.2%-51.0%) in the child ILI households. 180/310 (58.1%; 95%CI:51.7%-64.5%) of total child ILIs had time off education, 81/180 (45.0%; 95%CI:38.5%-51.5%%) taking ≥ 3 days. 59/310 (19.0%; 95%CI:17.0%-21.1%) had GP visits, 22/310 (7.1%; 95%CI:6.4%-7.8%) had GP telephone consultations, 48/310 (15.5%; 95%CI:13.8%-17.2%) received prescriptions, 234/310 (75.5%; 95%CI:67.1-83.8%) used OTC medications. ConClusions: Based on survey, approximately 1/3 of adult ILIs were related to prior household child ILI. ILI in a household often required absence from work and ILI in children often resulted in time off education. GP visits were the most frequent burden to the National Health Service. PIN117 CoPINg wIth methICIllIN resIstaNt staPhyloCoCCus aureus (mrsa) IN germaN rehabIlItatIoN CeNters -are the INCeNtIves aPProPrIate?objeCtives: Patients colonized with multidrug-resistant organisms, especially Methicillin resistant Staphylococcus aureus (MRSA), impose a risk on other patients and on health care professionals. In addition, they will suffer from substantial health problems when getting an infection. This contribution examines the incentives of German rehabilitation centers to implement screening strategies to stem nosocomial infections and the spread of MRSA. Methods: Relying on a decision tree analysis, the expected health care cost per capita is calculated for three strategies: (i) general screening, (ii) risk-based screening, both on admission, and (iii) no screening at all. Parameters are taken from the published literature. To handle uncertainty, multivariate sensitivity analyses are performed. Results: From the perspective of a rehabilitation center, the third strategy yields the lowest expected cost while the first one causes the highest cost. This ordering is robust with respect to sensitivity analysis. Thus, cost savings due to a lower number of MRSA infections are not sufficient to offset the cost of the test and further prevention measures applied to individuals with a posit...