A dietary cholesterol challenge study to assess Chlorella supplementation in maintaining healthy lipid levels in adults: a double-blinded, randomized, placebo-controlled study

Kim, Sangmi; Kim, Joohee; Lim, Yeni; Kim, You Jin; Kim, Ji Yeon; Kwon, Oran

doi:10.1186/s12937-016-0174-9

Cited by 21 publications

(14 citation statements)

References 22 publications

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“…et al 2016). As evidenced using clinical trials, both supplements reveal promising bioactive properties encompassing immunomodulatory, antihypertensive, antilipidemic, and hypoglycemic effects (Nielsen et al 2010;Kim et al 2016;Juszkiewicz et al 2018). This not only advocates the role of these products as functional foods but also supports their potential therapeutic use.…”

Section: ; Wellsmentioning

confidence: 79%

Essential and toxic elements in commercial microalgal food supplements

et al. 2018

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Arthrospira spp. (known commercially as Spirulina) and Chlorella spp., valued for their evidence-based nutritional and bioactive properties, are cultivated for the purpose of production of food supplements for worldwide distribution. However, the quality and safety of the final product depends on culturing and manufacturing conditions. The present study investigated the content of toxic elements (As species, Al, Cd, Hg, Ni, Pt, Pb, Cr (VI), rare earth elements) and minerals (Ca, Co, Cr, Cu, Fe, K, Na, Mg, Mn, P, Zn) in Chlorella (n = 10) and Spirulina (n = 13) food supplements registered in the European Union. Considering the most common recommended daily dosage 3.0, supplementation with any of the studied product would contribute significantly to mineral intake, with the exception of Fe which was found at high but acceptable levels in both Spirulina and Chlorella formulas. The majority of products revealed agreement between factual mineral content and that declared on the label, the only exception being Cu content in Chlorella products found to be significantly higher (> 130%). All studied supplements were found to have Cd, Hg, and Ni levels much below safety limits, although selected ones were characterized by increased content of Al, Pb, and inorganic As. No hexavalent Cr was detected in the studied products. The study highlights that microalgal supplements can be safe for consumers if appropriate measures are taken to ensure consumer safety, although it underlines the continuous need to monitor these products in order to fully eliminate those of low quality.

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Section: ; Wellsmentioning

confidence: 79%

Essential and toxic elements in commercial microalgal food supplements

et al. 2018

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“…An interesting point in this type of exercise is the improvement of maximum oxygen intake, which can be an important indicator of health promotion, along with body fat and weight loss. Kim tive role in maintaining serum cholesterol levels against high cholesterol food consumption (38).…”

Section: Discussionmentioning

confidence: 99%

Effect of Aerobic Training and C. vulgaris Intake on Lipid Profile and Leptin in Obese Women

Karbalamahdi

Abedi

Fatolahi

et al. 2019

Hormozgan medical journal

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Background: Regular physical activity can reduce the complications of obesity. Chlorella vulgaris (C. vulgaris) is recognized as a rich source of health promotion. Objectives: The aim of this study was to evaluate the effect of aerobic training and C. vulgaris intake on lipid profile and leptin in obese women. Methods: We randomly divided 32 obese women into control (C), aerobic training (AT), C. vulgaris (CV), and aerobic training plus C. vulgaris (AT+CV) groups. Interventions were performed for eight weeks. C. vulgaris was used at the dose of 1200 mg/day. The aerobic training included activities on a treadmill with 65%-80% of maximum heart rate (MHR) (three sessions/week). Blood samples were taken before and after the interventions. Results: The body weight, body mass index (BMI), leptin, triglyceride, cholesterol, HDL-C, and LDL-C significantly improved in the AT and AT+CV groups compared to the control group (P < 0.05). There was no significant difference between the AT and AT+CV groups (P > 0.05). Conclusions: Aerobic training can improve the lipid profile and leptin in obese women by reducing weight, increasing oxygen uptake, and improving lipid oxidation. Nevertheless, the effect of C. vulgaris was not detected individually. However, the effect of training may be due to the modification of exercise-induced responses by C. vulgaris properties. Therefore, there is a need for further investigation of C. vulgaris physiological function in the field of sports medicine.

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“…and Chlorella sp. have clinically shown the ability to positively affect lipid profiles, various immune variables, and have antioxidant capacities (Mao et al, 2005;Park et al, 2008;Ryu et al, 2014;Kim et al, 2016;Garcia et al, 2017).…”

Section: Food and Nutraceuticalsmentioning

confidence: 99%

Emerging Technologies in Algal Biotechnology: Toward the Establishment of a Sustainable, Algae-Based Bioeconomy

et al. 2020

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Mankind has recognized the value of land plants as renewable sources of food, medicine, and materials for millennia. Throughout human history, agricultural methods were continuously modified and improved to meet the changing needs of civilization. Today, our rapidly growing population requires further innovation to address the practical limitations and serious environmental concerns associated with current industrial and agricultural practices. Microalgae are a diverse group of unicellular photosynthetic organisms that are emerging as next-generation resources with the potential to address urgent industrial and agricultural demands. The extensive biological diversity of algae can be leveraged to produce a wealth of valuable bioproducts, either naturally or via genetic manipulation. Microalgae additionally possess a set of intrinsic advantages, such as low production costs, no requirement for arable land, and the capacity to grow rapidly in both large-scale outdoor systems and scalable, fully contained photobioreactors. Here, we review technical advancements, novel fields of application, and products in the field of algal biotechnology to illustrate how algae could present high-tech, low-cost, and environmentally friendly solutions to many current and future needs of our society. We discuss how emerging technologies such as synthetic biology, highthroughput phenomics, and the application of internet of things (IoT) automation to algal manufacturing technology can advance the understanding of algal biology and, ultimately, drive the establishment of an algal-based bioeconomy.

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A dietary cholesterol challenge study to assess Chlorella supplementation in maintaining healthy lipid levels in adults: a double-blinded, randomized, placebo-controlled study

Cited by 21 publications

References 22 publications

Essential and toxic elements in commercial microalgal food supplements

Essential and toxic elements in commercial microalgal food supplements

Effect of Aerobic Training and C. vulgaris Intake on Lipid Profile and Leptin in Obese Women

Emerging Technologies in Algal Biotechnology: Toward the Establishment of a Sustainable, Algae-Based Bioeconomy

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