Effects of ozone gas on skin flaps viability in rats: an experimental study

Güner, Mehmet Haşim; Görgülü, Tahsin; Olgun, Abdulkerim; Torun, Merve; Kargι, Eksal

doi:10.3109/2000656x.2016.1170024

Cited by 4 publications

(2 citation statements)

References 22 publications

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“…Similarly, Krkl et al [41] showed that ozonated olive oil improved neovascularization in rats when it was topically applied on skin flaps via VEGF upregulation. In addition, ozonated oil reduced doxorubicine-induced skin necrosis and injury as measured by a significant reduction of TNF-α, SOD, GSH-Px, and IL-1β [42] and by the enhanced flap viability in a rat model [43].…”

Section: Ozone Therapy and Skin Diseasesmentioning

confidence: 99%

The Biochemical and Pharmacological Properties of Ozone: The Smell of Protection in Acute and Chronic Diseases

Mauro

Cantarella

Bernardini

et al. 2019

IJMS

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Ozone therapy has been widely used in everyday clinical practice over the last few years, leading to significant clinical results in the treatment of herniated discs and pain management. Nevertheless, further studies have demonstrated its potential efficacy and safety under other clinical and experimental conditions. However, some of these studies showed controversial results regarding the safety and efficacy of ozone therapy, thus mining its potential use in an everyday clinical practice. To this regard, it should be considered that extensive literature review reported the use of ozone in a significant different dose range and with different delivery systems. The aim of the present review is to describe the various pharmacological effects of ozone in different organs and clinical conditions and to provide possible biochemical and molecular insights for ozone biological properties, thus providing a possible explanation for various controversial clinical outcomes described in the scientific literature.

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Section: Ozone Therapy and Skin Diseasesmentioning

confidence: 99%

The Biochemical and Pharmacological Properties of Ozone: The Smell of Protection in Acute and Chronic Diseases

Mauro

Cantarella

Bernardini

et al. 2019

IJMS

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“…Therefore, plastic surgeons give great attention to improve flap circulation prior to flap harvesting. For this reason, the effects of various pharmacological agents as well as different surgical modalities had been studied and discussed extensively in literature [1].…”

mentioning

confidence: 99%

Evaluation of Micro-Needling as a Flap Preconditioning Modality: A Split-Flap Study

Hussein

Zaki

Abdelkhakeq

et al. 2020

The Egyptian Journal of Plastic and Reconstructive Surgery

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Low-temperature argon plasma jet with cascading electrode technique for biological applications

Seyfi

Keshavarzi

Zahedi

et al. 2022

Sci Rep

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In this study, the design, performance, and characteristics of a low-temperature argon plasma jet with cascading electrode technique (APJCE) are presented. APJCE is designed based on a tip-ring structure with a cascading ring. The effect of plasma jet driven by repetitive high-voltage microsecond pulses in APJCE structure was measured qualitatively in local surface temperature detection system. Then, by applying the generated plasma jet to biological surface and measuring and characterizing the electrical parameters, we obtained a plasma jet, which is electrically and thermally in the cold plasma regime. Simulation of the electric field distribution in the nozzle also yielded similar results to the experimental results. Finally, by cascading electrodes, we guided the plasma column to the nozzle output so that the plasma temperature within four centimeters of the nozzle output is 37 °C. The resulting plasma jets were studied by atomic emission spectroscopy and the intensity of the spectral lines of the atmospheric argon plasma jet spectra was obtained as a final experimental result at the output.

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Effects of ozone gas on skin flaps viability in rats: an experimental study

Abstract: Ozone gas enhanced flap viability. No differences in flap viability were observed between the vegetable oil and vegetable oil with ozone peroxide groups. The greatest benefit ratios were found in the hemo-ozone therapy group.

Cited by 4 publications

References 22 publications

The Biochemical and Pharmacological Properties of Ozone: The Smell of Protection in Acute and Chronic Diseases

The Biochemical and Pharmacological Properties of Ozone: The Smell of Protection in Acute and Chronic Diseases

Evaluation of Micro-Needling as a Flap Preconditioning Modality: A Split-Flap Study

Low-temperature argon plasma jet with cascading electrode technique for biological applications

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