Definitions of intestinal failure and the short bowel syndrome

Pironi, Loris

doi:10.1016/j.bpg.2016.02.011

Cited by 174 publications

(208 citation statements)

References 44 publications

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“…Fluid disturbances are probably revealed faster and are better objectively defined by decreases in urine volume and sodium and by laboratory values (plasma electrolytes and creatinine) than nutritional deprivation (Table 4). It is worth noting that the 25th percentile of urine production in the L#10%WW group was as low as 420 g/d, whereas urine production .800 g/d would be recommended by most clinicians (26,27). Because urine creatinine was not measured, we do not know whether these patients experienced diminished creatinine excretion as an indication of dehydration and renal impairment.…”

mentioning

confidence: 93%

The use of metabolic balance studies in the objective discrimination between intestinal insufficiency and intestinal failure

Prahm

Brandt

Askov-Hansen

et al. 2017

The American Journal of Clinical Nutrition

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, which were equivalent to findings in research settings (differences of 3.6% and 8.7%; P = 0.65 and 0.60, respectively). Oral failure defined as energy intake ,130% of calculated BMR or WW intake ,40 g $ kg body weight -1 $ d -1 was seen in 71% and 82% of the 10% of patients with the lowest energy absorption and WW absorption, respectively. Conclusions: In clinical settings, the borderlines between INS and IF were not significantly different from those in research settings, even in an unselected patient population in which oral failure was also a predominant cause of nutritional dyshomeostasis. MBSs may be recommended to identify the individual patient in the spectrum from INS to IF, to objectivize the cause of nutritional dyshomeostasis (oral failure, malabsorption, or both), and to quantify the effects of treatment. Am J Clin Nutr 2017;106:831-8.

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mentioning

confidence: 93%

The use of metabolic balance studies in the objective discrimination between intestinal insufficiency and intestinal failure

Prahm

Brandt

Askov-Hansen

et al. 2017

The American Journal of Clinical Nutrition

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“…Short bowel syndrome (SBS) refers to a group of symptoms related to the malabsorptive state following massive small‐bowel resections . Intestinal barrier dysfunction, including the disruption of mechanical barrier, luminal bacteria overgrowth, and translocation, has been well recorded in SBS .…”

Section: Introductionmentioning

confidence: 99%

Milk Fat Globule Membrane Inhibits NLRP3 Inflammasome Activation and Enhances Intestinal Barrier Function in a Rat Model of Short Bowel

Niu

et al. 2018

J Parenter Enteral Nutr

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“…In such situations the introduction of enteral nutrition can damage the surrounding tissues, worsen the healing ability and, most importantly, can worsen water and electrolyte disturbances. 8 If the patient is cachectic due to malnutrition, we begin our nutritional intervention with partial energy supply (50% of daily energy expenditure), calculated on the basis of energy requirement of 30-35 kcal/kg bodyweight and protein requirement at the level of 1.5-2 g/kg bodyweight. These allow us to optimally support the inflammatory response of the organism whilst minimising the risk of metabolic complications described above.…”

Section: Discussionmentioning

confidence: 99%

Role of nutritional intervention in negative pressure wound therapy (NPWT). Case report of patient treated by 'open abdomen' method.

Kuczyńska

2017

NPWTJ

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Abstract-Introduction: Wound healing process depends on many factors. As it has been proved many times before, nutrition is one of the key factors in wound healing therapy. When there is an insufficient supply of nutrients and malnutrition, wound healing processes slow down and the inflammatory phase is prolonged, which requires high energy expenditure and as a consequence, may lead to the loss of lean body mass and the development of sarcopenia and cachexia. This promotes the formation of non-healing chronic wounds.In this paper we would like to emphasize the role of nutrition, as an integral part of wound healing processes, which should encompass the current metabolic needs associated with patient's clinical condition.Case report: This case describes a young male patient with gastrointestinal tract insufficiency and an extensive postoperative wound treated by the open abdomen method. In the course of increased catabolism, water and electrolyte loss and disturbances as well as nutritional insufficiencies, body mass loss and progressive cachexia occurred in this patient and, as a consequence, the wound healing processes was significantly diminished.Conclusions: Inducing and maintaining the anabolic processes in the organism and control of the enhanced catabolism in response to metabolic stress or injury are essential actions in optimizing the treatment and healing process. These are possible to achieve by the early introduction of balanced and individualized nutritional treatment regimens, provision of the energy and appropriate nutrients, which enables the restoration of lean body mass and stimulation of the healing processes.

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Definitions of intestinal failure and the short bowel syndrome

Cited by 174 publications

References 44 publications

The use of metabolic balance studies in the objective discrimination between intestinal insufficiency and intestinal failure

The use of metabolic balance studies in the objective discrimination between intestinal insufficiency and intestinal failure

Milk Fat Globule Membrane Inhibits NLRP3 Inflammasome Activation and Enhances Intestinal Barrier Function in a Rat Model of Short Bowel

Role of nutritional intervention in negative pressure wound therapy (NPWT). Case report of patient treated by 'open abdomen' method.

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