Effect of xylitol varnishes on remineralization of artificial enamel caries lesions in situ

Eficácia de um dentifrício sem flúor no controle de Streptococcus mutans in vitro

“…Em outro estudo, utilizando modelo de biofilme multiespécie in vitro e xilitol nas concentrações de 1 a 3%, houve redução da formação do biofilme, comparado ao controle. 16 Cardoso et al (2016) 17 verificaram que um verniz experimental contendo 20% de xilitol sem flúor apresentou potencial remineralizador em ensaio realizado in situ.…”

“…9,10 O efeito clínico de dentifrícios não fluoretados contendo agentes antimicrobianos ainda é controverso na literatura. [11][12][13][14] Estudos laboratoriais in vitro em geral têm comprovado a eficácia do xilitol em cepas de S. mutans, 9,[15][16][17] no entanto, outros estudos somente verificam sua ação, quando associado a fluoretos ou outros agentes anitimicrobianos. [18][19][20][21][22] Portanto, o objetivo deste estudo foi avaliar a eficácia in vitro de um dentifrício não fluoretado (marca Orgânico Natural®) na inibição da cepa de S. mutans, um dos principais agentes etiológicos no processo da cárie dentária.…”

Polyols and remineralisation of enamel subsurface lesions

“…Based on these findings the authors speculated that these polyols "may favourably govern remineralisation of carious lesions". The belief that xylitol can remineralise enamel subsurface lesions by forming calcium complexes is still apparent in the more recent literature [31][32][33] although unequivocal evidence to support the claim is still lacking. The concentrations and conditions used by Makinen and Soderling [21] to define extremely weak calcium-polyol complexes are not physiologically relevant and cannot be extrapolated to the conditions in saliva upon release of the polyols on gum chewing which produce much lower peak salivary concentrations for only a few minutes.…”

Remineralizing Effect of Xilitol, Juniperus Communis and Camellia Sinensis Added to a Toothpaste: An In Vitro Study

“…Remineralization is a net gain of ions towards the dental tissues, which replaces the loss due to the demineralization process. This occurs through a physical-chemical process that includes the supersaturation of ions in the solution in relation to enamel, the formation of nucleus and crystals (6,7). Since the control of dental caries remains a challenge (8) as one of the main public health problems in the world, its negative impacts should not be underestimated.…”