Choque séptico secundario a fiebre por chikungunya no congénita en un lactante menor: caso clínico

Abstract

Chikungunya is a disease in which the manifestations in neonates and young infants can be severe, and even fatal. It is important to suspect it in this age group at risk of vector contact, in the presence of fever without apparent source of infection and cutaneous manifestations. It is important to use the antipyretics cautiously, considering the possibility of aggravating the underlying infection, and the potential hepatic and haematological damage.

Chikungunya Immunopathology as It Presents in Different Organ Systems

“…There are several different types of cutaneous or mucocutaneous presentations of CHIKV, reported in all age groups and of varying severity [109][110][111][112][113][114][115][116][117][118][119][120][121][122]. As high as 50% of CHIKV patients will have some sort of mucocutaneous presentation, most commonly a maculopapular rash, which shows up 3-5 days post fever onset and alleviates 3-4 days later [121].…”

Chikungunya in Infants and Children: Is Pathogenesis Increasing?

“…In 2014–2015, CHIKV-WH invaded Mexico and in July 2015 caused an outbreak in the Yucatan region. Here, a one-month old infant was admitted to hospital with CHIKV-WH infection [134]. He presented with fever, lethargy, an erythematous maculopapular rash, and was diagnosed with septic shock secondary to CHIKF [134].…”

“…Here, a one-month old infant was admitted to hospital with CHIKV-WH infection [134]. He presented with fever, lethargy, an erythematous maculopapular rash, and was diagnosed with septic shock secondary to CHIKF [134]. The infant soon developed poor perfusion and was connected to a ventilator [134].…”

“…He presented with fever, lethargy, an erythematous maculopapular rash, and was diagnosed with septic shock secondary to CHIKF [134]. The infant soon developed poor perfusion and was connected to a ventilator [134]. A few hours later, he developed tonic-clonic seizures and fatal septic shock [134].…”

“…The infant soon developed poor perfusion and was connected to a ventilator [134]. A few hours later, he developed tonic-clonic seizures and fatal septic shock [134]. The island of Curacao experienced an outbreak in 2014 in which three vertically infected neonates experienced severe CNS complications [74].…”