Antihyperlipidemic Effect of Syrian Mesquite (<i>Prosopis farcta</i>) Root in High Cholesterol Diet–Fed Rabbits

Saidi, Mohammad R.; Farzaei, Mohammad Hosein; Miraghaee, Shahram; Babaei, Atefeh; Mohammadi, Bahareh; Bahrami, Mohammad; Bahrami, Gholamreza

doi:10.1177/2156587215627552

Cited by 17 publications

(10 citation statements)

References 20 publications

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“…41 Aqueous root extract reduced lipids in the blood of high cholesterol diet rabbits and had aorta protective effect. 42,43 Aqueous root extracts were active lipids lowering in rabbits livers. 44…”

Section: Antihyperlipidemicmentioning

confidence: 97%

Antifungal and anti-termite activities, total phenolic content of Prosopis Farcta extracts; and attempts to develop weed biocontrol method against it

Azab

2019

ECB

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Prosopis farcta is a widespread weed in the Near East and its an invasive plant of southwestern parts of the USA. Despite being sufficiently studied in the past, some of its activities were not published. In this research, we studied the antifungal and anti-termite activities of four extracts of the plant aerial parts: aqueous, ethanolic, ethyl acetate and hexane. In addition, since the published reports of total phenolic content (TPC) are not consistent, we tested this as well. We also tested the potential of the aqueous extract of Carya illinoinensis as possible weed biocontrol against P. farcta. The n-Hexane extract had the highest antifungal and anti-termite activities. TPC was found around 13.9 mg of gallic acid equivalent for 1 g of dry ethanolic extract (highest). The attempts to use an aqueous extract of C. illinoinensis for weed biocontrol of P. farcta achieved very limited success

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Section: Antihyperlipidemicmentioning

confidence: 97%

Antifungal and anti-termite activities, total phenolic content of Prosopis Farcta extracts; and attempts to develop weed biocontrol method against it

Azab

2019

ECB

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“…Different species of the Prosopis genus have been utilized for gum, paint and cordage (6) and as dietary supplements for feeding ruminants (7) as well as for medicinal purposes. Beans and leaves of P. farcta have traditionally been used for the treatment of some diseases and disorders such as diabetes (8,9) healing lesions (10), diarrhea, and colds (11).…”

Section: Introductionmentioning

confidence: 99%

Some anti-diabetic properties of Prosopis farcta extracts in alloxan induced diabetic in adult rats

Mohammed¹,

Kakey²,

Farimani³

2020

IJVS

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Prosopis farcta is belonged to Mimosaceae family, commonly known as mesquite. It was chosen to investigate their effect on α-glucosidase inhibitory activity (in-vitro), serum glucose and liver functions. Roots, fruits, and leaves of P. farcta, were extracted by n-hexane, ethyl acetate, and methanol. α-glucosidase inhibition was analyzed by using ELISA technique then half maximal inhibitory concentration IC50 was found. The blood glucose levels were determined with a glucose analyzer model. The serum alkaline phosphatase (ALP), Alanine transaminase (ALT), aspartate aminotransferase (AST) and serum total bilirubin (TB) were estimated by using the Cobas diagnostic kit with a fully automated chemical analyzer. Diabetes was done by a single dose of 120 mg alloxan/kg b.w with subcutaneously injection. Ethyl acetate extracts of P. farcta showed the higher α-glucosidase inhibitory activity, and the best one was root extract. Treatments of the alloxan-induced diabetes rats were done by daily oral administration of different concentrations with P. farcta extracts of ethyl acetate for 28 days and the dose 200 mg/kg BW was the effective one. The root extract was the best one for reduction of serum glucose followed by leaves then fruits. Administration of root extract of P. farcta showed a decrease in the levels of ALP and TB in alloxan-induced diabetes rats. The fruit extract of P. farcta showed decreasing in the level of ALP in alloxan-induced diabetes rats. In conclusion, the P. farcta extracts for ethyl acetate have properties of hypoglycemic effect as well as improving some parameters related with diabetic complications of liver functions.

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“…A significant decrease in TC, triglyceride, HDL, LDL, and VLDL levels was recorded in rabbits administered with P. farcta root. Thus, this extract has beneficial effects on cardiovascular health [82]. The effect of P. farcta plant extract on thoracic aorta was evaluated.…”

Section: Cardiovascular Disordersmentioning

confidence: 99%

Prosopis Plant Chemical Composition and Pharmacological Attributes: Targeting Clinical Studies from Preclinical Evidence

et al. 2019

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Members of the Prosopis genus are native to America, Africa and Asia, and have long been used in traditional medicine. The Prosopis species most commonly used for medicinal purposes are P. africana, P. alba, P. cineraria, P. farcta, P. glandulosa, P. juliflora, P. nigra, P. ruscifolia and P. spicigera, which are highly effective in asthma, birth/postpartum pains, callouses, conjunctivitis, diabetes, diarrhea, expectorant, fever, flu, lactation, liver infection, malaria, otitis, pains, pediculosis, rheumatism, scabies, skin inflammations, spasm, stomach ache, bladder and pancreas stone removal. Flour, syrup, and beverages from Prosopis pods have also been potentially used for foods and food supplement formulation in many regions of the world. In addition, various in vitro and in vivo studies have revealed interesting antiplasmodial, antipyretic, anti-inflammatory, antimicrobial, anticancer, antidiabetic and wound healing effects. The phytochemical composition of Prosopis plants, namely their content of C-glycosyl flavones (such as schaftoside, isoschaftoside, vicenin II, vitexin and isovitexin) has been increasingly correlated with the observed biological effects. Thus, given the literature reports, Prosopis plants have positive impact on the human diet and general health. In this sense, the present review provides an in-depth overview of the literature data regarding Prosopis plants’ chemical composition, pharmacological and food applications, covering from pre-clinical data to upcoming clinical studies.

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Antihyperlipidemic Effect of Syrian Mesquite (Prosopis farcta) Root in High Cholesterol Diet–Fed Rabbits

Cited by 17 publications

References 20 publications

Antifungal and anti-termite activities, total phenolic content of Prosopis Farcta extracts; and attempts to develop weed biocontrol method against it

Antifungal and anti-termite activities, total phenolic content of Prosopis Farcta extracts; and attempts to develop weed biocontrol method against it

Some anti-diabetic properties of Prosopis farcta extracts in alloxan induced diabetic in adult rats

Prosopis Plant Chemical Composition and Pharmacological Attributes: Targeting Clinical Studies from Preclinical Evidence

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