Prognostic Impacts of Metabolic Syndrome in Patients With Chronic Heart Failure　– A Multicenter Prospective Cohort Study –

The influence of metabolic syndrome coexistence on the prognosis of patients with heart failure without atrial fibrillation. Analysis of Polish data from the pilot survey for the ESC Heart Failure Registry

“…In our study, as far as patients without AF were concerned, coexistence of MS was related to a 56% higher relative risk of death. This observation remains consistent with the previously presented results of the studies by Tamariz et al [7] and Tadaki et al [9], but simultaneously appears to contradict the results of Perrone-Filardi et al [10]. Interaction analysis, however, showed that the negative impact of MS on the survival of HF patients without AF resulted primarily from the coexistence of diabetes and hypertension.…”

“…Yoon et al [8], however, observed lower mortality in patients with MS than in patients without MS (4.9% vs. 8.3%, p < 0.001). By contrast, Tadaki et al [9] observed a 28% (HR 1.28, 95% confidence interval 1.06-1.54, p = 0.011) increased risk of death or cardiovascular event in the case of coexisting HF and MS, but only in men. Perrone-Filardi et al [10] observed comparable survival in patients without MS and diabetes and in those with MS and coexisting diabetes.…”

Diets high in vegetables, fruits, cereals, and tubers as a protective factor for metabolic syndrome in bank employees

“…The pattern “vegetables, fruits, cereals, and tubers” was a protective factor against MetS, unlike the “sweets and snacks” and “traditional and protein” patterns, possibly due to the nutritional composition of this dietary pattern. The protection attributed to the pattern “vegetables, fruits, cereals, and tubers” against MetS might be due to the interaction of factors that prevented the central deposit of fat and consequently of insulin resistance and its metabolic complications, 36 consistent with the association of this dietary pattern with lower WC in bank employees. This effect probably occurred due to the antioxidant and anti-inflammatory capacity of foods belonging to this pattern.…”

Gamma-Glutamyl Transferase as a Risk Biomarker of Cardiovascular Disease ― Does It Have Another Face? ―

“…8,16,17 Although the serum GGT level was an independent risk factor after adjustment for metabolic factors in previous studies, 8-10 metabolic syndrome itself can affect the incidence and prognosis of HF. 17 As many biomarkers linked to the metabolic syndrome have been reported, the incremental value of GGT to predict CVD should be revealed in addition to its independence of metabolic factors.…”