Protein ligand-tethered synthetic calcium indicator for localization control and spatiotemporal calcium imaging in plant cells

Piperazine and morpholine are important heterocyclic structures, which are widely used in the discovery of agrochemicals. Piperazine and morpholine rings are often used as active substructures or bridges to design and synthesize new agrochemicals. In the past decade, piperazine and morpholine compounds have made rapid progress in the research and development of new pesticides, especially in the discovery of fungicides and antibacterial agents. In the future, more piperazine and morpholine pesticides may be commercialized. However, there is no comprehensive review on the use of piperazine and morpholine derivatives in the creation of new agrochemicals. Therefore, we systematically reviewed the application of piperazine and morpholine active compounds in the creation of new pesticides in the past 12 years. This paper not only summarizes the biological activities of piperazine and morpholine compounds, but also discusses the structure–activity relationship, physiological and biochemical changes, and mechanism of action. This work aims to provide inspiration and ideas for the discovery of new agrochemicals of piperazine and morpholine.

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Research progress of piperazine and morpholine derivatives in the discovery of agricultural chemicals

Zhang

Xing

Zou

et al. 2023

Journal of Heterocyclic Chem

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Molecule fluorescent probes for sensing and imaging analytes in plants: Developments and challenges

Yang

Zhang

et al. 2023

Coordination Chemistry Reviews

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Design and synthesis of a second-generation ligand-tethered calcium indicator for plant cell biology based on the fundamental analyses of the structure and physical property

2017

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Protein ligand-tethered synthetic calcium indicator for localization control and spatiotemporal calcium imaging in plant cells

Cited by 3 publications

References 30 publications

Research progress of piperazine and morpholine derivatives in the discovery of agricultural chemicals

Research progress of piperazine and morpholine derivatives in the discovery of agricultural chemicals

Molecule fluorescent probes for sensing and imaging analytes in plants: Developments and challenges

Design and synthesis of a second-generation ligand-tethered calcium indicator for plant cell biology based on the fundamental analyses of the structure and physical property

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