“…Critically ill human and animal patients often exhibit signs of coagulopathy, with a hypercoagulable state preceding deterioration into disseminated intravascular coagulopathy (DIC). Several studies have documented that horses with ischemic or inflammatory gastrointestinal disease are at increased risk for coagulopathy that may progress to DIC and death (Cesarini, Cotovio, Rios, Armengou, & Jose‐Cunilleras, ; Dolente, Wilkins, & Boston, ; Epstein, ; Epstein, Brainard, Giguere, Vrono, & Moore, ). Therefore, in patients with potential hypercoagulability, treatment with COX‐1‐specific inhibitors (e.g., aspirin) might be indicated (Epstein, ).…”