Determination of cytotoxicity of traditional Chinese medicine herbs, Rhizoma coptidis, Radix scutellariae, and Cortex phellodendri, by three methods

High-efficient extraction of principal medicinal components from fresh Phellodendron bark (cortex phellodendri)

“…Therefore, the efficient extraction of medicinal components from Phellodendron bark was focused by researches (Boost et al, 2016). The widely used extraction methods were soxhlet extraction, distillation and ultrasonic extraction, and the extraction solvents were water, organic solvents and their combinations (Wang et al, 2015, Chen et al, 2014).…”

Effects of Lead Phytochemicals of Radix Scutellariae on Acanthamoeba

“…31,32 Some compounds have been shown to have useful properties and have been used in experimental treatments for cancer. 33 R. scutellariae has previously been shown to have minimum cytotoxic effects on HCEC, 28 and ingestion was not found to be harmful to rats or dogs. 31 The herb has been used in TCM for many years seemingly without toxicity problems, but lack of toxicity of the individual agents requires confirmation.…”

“…There was no significant increase in viability, apoptosis, or early necrosis in a comparison between HCEC and control cells exposed to the extract. 28 Determining the lead phytochemicals in R. scutellariae and testing those compounds at known concentrations against Acanthamoeba could demonstrate whether the phytochemicals had potential as therapeutic or preventive agents incorporated into multipurpose contact lens solutions. This study tested the effects of four main phytochemicals, determined by mass spectrometry/gas chromatography from an extract of R. scutellariae alone and in combination on two pathogenic Acanthamoeba species, and investigated the compatibility of these agents with existing MPS for RGP lenses.…”

We are being myopic about myopia control

“…Perhaps light transmission and assessed by José M Artigas could contribute to the outdoor environmental myopia progression retardation effects [15]. Who knows, future research may identify Traditional Chinese Medicine herbs such as those examined by Maureen Boost, may prove beneficial [16].…”