Acute human bocavirus infection in MDS patient, Cologne, Germany

Influenza and Viral Pneumonia

“…67,68 It has been detected in acute respiratory illness of adults with immunosuppression and chronic lung disease. 69,70 A study showed that it can be often identified in the sinus tissue specimens of adult patients with chronic sinusitis. 71…”

Severe Human Bocavirus–Associated Pneumonia in Adults at a Referral Hospital, Seoul, South Korea

“…Information on severe HBoV-associated pneumonia in adults is limited. Five cases of severe HBoV-associated pneumonia have been reported to date ( 8 – 12 ), which included 3 cases from the same facility in Germany ( 9 , 10 , 12 ). Of the 5 patients, 3 had hematologic malignancy and 1 had cystic fibrosis.…”

“…It can also be associated with the acute exacerbation of chronic obstructive pulmonary disease (7). Recently, a few case reports have shown that HBoV can be associated with life-threatening pneumonia (8)(9)(10)(11)(12). However, severe HBoV-associated pneumonia has not been reported in a case series, and little is known about the characteristics of HBoV-associated pneumonia in critically ill adult patients.…”

Severe Human Bocavirus 1 Respiratory Tract Infection in an Immunodeficient Child With Fatal Outcome

“…HBoV1 may cause also life-threatening complications of lower respiratory tract infection including emphysema, pneumomediastinum, pneumothorax and acute respiratory failure [15 -18]. In addition, both Sadeghi et al [19] and Krakau et al [20] described immunocompromised adult patients suffering from an advanced myelodysplastic syndrome with severe HBoV1 pneumonia with fatal outcome. Further fatal cases associated with HBoV1 infection were described in an adult and a pediatric patient with underlying lung diseases [21,22].…”