Abdominal alterations in disseminated paracoccidioidomycosis: computed tomography findings

Vermelho, Marli; Correia, A. S.; Michailowsky, Tânia Cibele de Almeida; Suzart, Elizete Kazumi Kuniyoshi; Ibanês, Aline Santos; Almeida, Lanamar Aparecida; Khoury, Zarifa; Barba, Mario Flores

doi:10.1590/0100-3984.2013.0025

Cited by 16 publications

(13 citation statements)

References 13 publications

(47 reference statements)

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“…Similarly, calcified lymph nodes were reported in three (11.5%) patients in a series of 26 cases of paracoccidioidomycosis who underwent abdominal CT 8 . However, this previous study did not describe the current or previous use of medication to treat paracoccidioidomycosis.…”

Section: Discussionmentioning

confidence: 69%

Paracoccidioidomycosis in a liver transplant recipient

Lima

Bezerra

Siqueira

et al. 2017

Rev. Soc. Bras. Med. Trop.

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Paracoccidioidomycosis is a granulomatous systemic mycosis that is endemic in Latin America; it is an extremely rare infection following solid organ transplantation. In this study, we describe the first report of disseminated paracoccidioidomycosis in a 3-year-old girl who underwent liver transplantation 2 years previously. The radiologic diagnosis and patient follow-up are described. In addition, we review the clinical evolution and treatment regimens for this infection.

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Section: Discussionmentioning

confidence: 69%

Paracoccidioidomycosis in a liver transplant recipient

Lima

Bezerra

Siqueira

et al. 2017

Rev. Soc. Bras. Med. Trop.

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“…Albumin levels significantly increased the area under the curve lethal cases affecting unusual organs and tissues with no clinical evidence were also observed in this study, confirming that the yeasts are capable to invade every tissue of the human body. [17][18][19][20][21][22][23][27][28][29][30][31] The extent of the elapsed time since the appearance of the first symptoms of PCM until the admission in a specialised centre did not interfere in the development of complications of the disease.…”

Section: Discussionmentioning

confidence: 99%

Acute‐subacute paracoccidioidomycosis: A paediatric cohort of 141 patients, exploring clinical characteristics, laboratorial analysis and developing a non‐survival predictor

Romaneli

Tardelli

Tresoldi

et al. 2019

Mycoses

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Summary The acute‐subacute form of paracoccidioidomycosis (PCM) is a severe systemic mycosis that affects children and adolescents from endemic regions, leading to generalised lymphadenopathy, fever, weight loss, anaemia, eosinophilia, hypoalbuminemia and hypergammaglobulinemia. The objective of this study is to describe the clinical and laboratorial characteristics of acute‐subacute PCM, to determine a mortality risk factor and to propose a test for non‐survival hazard related to the disease. Children and adolescents diagnosed with PCM, under 15 years were included in the study. Their epidemiological, clinical and laboratorial data were obtained from the hospital records. Descriptive analysis, comparison of means, univariate logistic regression, multivariate logistic regression and a ROC curve were performed in order to identify significant information (P < .05). Through a period of 38 years, 141 children and adolescents were diagnosed with acute‐subacute PCM. The main antifungal agent used for the treatment was sulfamethoxazole‐trimethoprim (SMX‐TMP). The complication rate was 17%, the relapse rate was 7.8% and the mortality rate was 5.7%. A low albumin dosage was identified as a predictor factor for mortality. The cut‐off for serum albumin was 2.18 g/dL, above which, the survival rate is 99.1%. Thus, simple clinical and laboratorial examinations may lead to the diagnosis of acute‐subacute PCM, and the beginning of the treatment is encouraged even before the isolation of the fungus in biological samples, preventing unfavourable outcomes. Patients with an albumin dosage ≤ 2.18g/dL must receive special attention, preferably hospitalised, during the first four weeks of treatment for presenting an elevated mortality hazard.

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“…Signs of peritonitis can indicate cecal perforation with pneumoperitoneum ( 6 ) , especially when the distension is greater than 12 cm and lasts for more than six days. For evaluating diseases of the colon, CT has been shown to be the method of choice ( 7 - 11 ) . In Ogilvie’s syndrome, CT is a useful for identifying the obstruction and determining the underlying cause ( 12 ) , the main findings being dilation extending from the cecum to the transverse colon, with a transition zone in the splenic flexure, where the caliber of the adjoining loop is considerably smaller.…”

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confidence: 99%