254 The sun protective behaviors and attitudes of early childhood programs in Illinois

Abstract

The red meat allergy caused by tick bites are increasing worldwide. It is known that IgE epitope of major red meat allergens is galactose-1,3-galactose (a-Gal). Thus, the patients with red meat allergy have a high risk to develop anaphylaxis to taking cetuximab that chimeratype monoclonal antineoplastic drug, because it also contains a-Gal, and its cross-reaction. The a-Gal specific IgE (sIgE) test by CAP-fluoro-enzyme immunoassay (FEIA) is one of the most sensitive examination to identify the patients with red meat allergy. In this study, we aimed to evaluate the prevalence of sensitization against a-Gal in Shimane prefecture that the endemic area of Japanese spotted fever and Miyagi prefecture that the area with lowincidence of Japanese spotted fever. We enrolled 200 patients from