Association of Markers of Inflammation with Sleep and Physical Activity Among People Living with HIV or AIDS

Wirth, Michael D.; Jaggers, Jason R.; Dudgeon, Wesley D.; Hébert, James R.; Youngstedt, Shawn D.; Blair, Steven N.; Hand, Gregory A.

doi:10.1007/s10461-014-0949-y

Cited by 38 publications

(31 citation statements)

References 74 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This may also explain why we did not find a strong correlation between the composite OSA risk score and fatigue score. The pathogenesis of OSA in HIV may also be driven by inflammatory cytokines, 21,39,40 resulting in impaired neuronal control of upper airway musculature during sleep. In addition, other molecular and genomic attributes of HIV 41,42 may also explain the occurrence of certain sleep disorders in this population.…”

Section: Sleep Apnea and Fatigue In Hiv 593mentioning

confidence: 99%

Sleep Apnea Symptoms as a Predictor of Fatigue in an Urban HIV Clinic

Goswami

Baker

Wang

et al. 2015

AIDS Patient Care and STDs

View full text Add to dashboard Cite

Fatigue is common among persons living with HIV (PLWH), and risk factors for obstructive sleep apnea (OSA) such as older age and obesity are increasingly prevalent. Studies of OSA among PLWH are lacking, so we aimed to characterize OSA symptoms and associated clinical consequences (e.g., fatigue) among a contemporary population of PLWH. Self-administered surveys containing 23 items that included self-reported snoring, witnessed apneas, estimated sleep duration, the Epworth Sleepiness Score (ESS), and the FACIT-Fatigue score were mailed to PLWH receiving care at an urban HIV clinic. Clinical/demographic data were collected from the medical record. Multivariable linear regression models were created to study relationships between fatigue, clinical variables, and OSA symptoms. Of 535 surveys, 203 (38%) responded. Eight patients (3.9%) had known OSA. Among those without known OSA, mean respondent characteristics included: age 47 years; 80% male, 41% African American, 48% Caucasian, BMI 26.4 kg/m 2 , duration of HIV diagnosis 12 years, 93% on antiretroviral therapy, and 81% with <50 HIV RNA copies/mL. 27% reported snoring, 24% reported witnessed apneas, and 38% had excessive daytime sleepiness. Witnessed apnea was the strongest independent predictor of fatigue (lower FACIT-Fatigue score; b = -6.49; p < 0.001); this difference of 6.49 points exceeds the accepted minimal clinically important difference of 3.0 points. Other predictors included opioid use (b = -5.53; p < 0.001), depression (b = -4.18; p = 0.02), antidepressant use (b = -4.25; p = 0.02), and sleep duration < 6 h (b = -3.42; p = 0.02). Our data strongly support the need for increased efforts directed at OSA screening and treatment in PLWH.

show abstract

Section: Sleep Apnea and Fatigue In Hiv 593mentioning

confidence: 99%

Sleep Apnea Symptoms as a Predictor of Fatigue in an Urban HIV Clinic

Goswami

Baker

Wang

et al. 2015

AIDS Patient Care and STDs

View full text Add to dashboard Cite

show abstract

“…Trata-se de um processo ativo envolvendo múltiplos e complexos mecanismos fisiológicos e comportamentais em vários sistemas e regiões do sistema nervoso central (SNC). O sono normal é constituído pela alternância dos estágios REM (movimentos rápidos dos olhos) e NREM, caracterizado pelo sono profundo e de descanso (13)(14) .…”

Section: Discussionunclassified

Diagnósticos de enfermagem do domínio atividade/repouso em pessoas vivendo com aids: transversal

et al. 2018

View full text Add to dashboard Cite

Aim: To identify the nursing diagnoses of the activity/rest domain of NANDA-I Taxonomy II and to analyze the association between the most frequent diagnoses and their defining characteristics, related factors/risk in people living with AIDS. Method: This is a cross-sectional and descriptive study using a quantitative approach. It was performed with 113 patients from March to September 2014. Data were collected using two validated instruments for anamnesis and physical examination. For the elaboration of the diagnoses, the Risner model was followed. And, for purposes of statistical association, the Chi-Square and Fisher tests were used. Results: We identified 30 diagnoses, and only six had a statistically significant association with their components: impaired sleep pattern; fatigue; insomnia; risk of ineffective renal perfusion; impaired walking; deficit in self-care for the bath. Conclusion: The diagnoses with their associated components provide guidance for the elaboration of nursing interventions as a priority.

show abstract

“…Greater quality of social relationships [7] and life satisfaction has also been reported comparably to non-exercising PLHIV [8]. Lastly, some studies evidenced the ability of exercise to better antiretroviral therapy adherence [9] and to hinder anti-inflammatory consequences [10]. …”

Section: Introductionmentioning

confidence: 99%

Exercise stereotypes and health-related outcomes in French people living with HIV: development and validation of an HIV Exercise Stereotypes Scale (HIVESS)

Gray

Falzon

Bergamaschi

et al. 2016

Health Qual Life Outcomes

View full text Add to dashboard Cite

BackgroundThe main objective of the current study was to develop and validate a French exercise stereotype scale for people living with HIV (PLHIV) in order to gain visibility to the possible barriers and facilitators for exercise in PLHIV and thus enhance their quality of life.MethodsA series of four complementary studies was carried out with a total sample of 524 participants to: (a) develop a preliminary version of the HIV Exercise Stereotype Scale (HIVESS) (Stage 1), (b) confirm the factorial structure of the instrument (Stage 2), (c) evaluate the stability of the instrument (Stage 3), and (d) examine the construct and divergent validity of the scale (Stage 4).ResultsResults provided support for a 14-item scale with three sub-scales reporting stereotypes related to exercise benefits, exercise risks and lack of capacity for exercise with Cronbach’s alphas of .77, .69 and .76 respectively. Results showed good factorial structure, strong reliability and indicators of convergent validity relating to self-efficacy, exercise and quality of life.ConclusionThe HIVESS presented satisfactory psychometric properties, constitutes a reliable and valid instrument to measure exercise stereotypes among PLHIV and has applications for future research and clinical practice.

show abstract

Association of Markers of Inflammation with Sleep and Physical Activity Among People Living with HIV or AIDS

Cited by 38 publications

References 74 publications

Sleep Apnea Symptoms as a Predictor of Fatigue in an Urban HIV Clinic

Sleep Apnea Symptoms as a Predictor of Fatigue in an Urban HIV Clinic

Diagnósticos de enfermagem do domínio atividade/repouso em pessoas vivendo com aids: transversal

Exercise stereotypes and health-related outcomes in French people living with HIV: development and validation of an HIV Exercise Stereotypes Scale (HIVESS)

Contact Info

Product

Resources

About