Ovarian teratoma in an equine fetus: a case report

Gamba, Conrado de Oliveira; Damasceno, Karine Araújo; Rocha, Sérgio Schwarz da; Mendes, Heloisa Maria Falcão; Faleiros, Rafael Resende; Cassali, Geovanni Dantas

doi:10.1080/01652176.2014.954064

Cited by 3 publications

(3 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Along with the three confirmed cases of ovarian teratoma in the present study, the authors can find reports of 14 other teratomas (Abraham, 1968; Bosu et al., 1982; Catone et al., 2004; Damodaran & Ramachandran, 1975; Fiala et al., 2011; Fujimoto & Sakai, 1955; Gamba et al., 2014; Gonzalez et al., 2015; Lefebvre et al., 2005; Panciera et al., 1991; Singh et al., 2019; Vanhaesebrouck et al., 2010) making a total of 17 cases. Three of these cases were chance findings from abattoir specimens, two were cases where the breed was not recorded.…”

Section: Discussionsupporting

confidence: 83%

Equine ovarian teratomas: Diagnostic challenges illustrated by case reports

Duarte

Allen

Guimei

et al. 2021

Equine Veterinary Education

View full text Add to dashboard Cite

Summary Teratomas are the most common germ cell tumours to afflict the ovaries of the mare, even though they occur rarely. They are often found incidentally during routine ultrasonographic examinations of the mare’s ovaries and are usually asymptomatic. Their ultrasonographic appearance varies, but they commonly present with characteristic echogenicity signs. However, before a presumptive diagnosis of a teratoma can be made, the suspect ovary, along with the rest of the reproductive tract, should be examined ultrasonographically on several occasions to confirm that the unusual structure maintains its appearance as a teratoma. This paper discusses three confirmed cases of ovarian teratoma and two cases where the ultrasonographical appearance of an ovary, combined with clinical signs, initially suggested a teratoma, but was then ruled out when the ovary had a normal appearance at subsequent examinations.

show abstract

Section: Discussionsupporting

confidence: 83%

Equine ovarian teratomas: Diagnostic challenges illustrated by case reports

Duarte

Allen

Guimei

et al. 2021

Equine Veterinary Education

View full text Add to dashboard Cite

show abstract

“…Nonetheless, rare neoplasms are documented, including a case of metastatic ovarian teratocarcinoma in a 3-years-old Quarter Horse mare ( 9 ). Conversely, ovarian teratomas are the most prevalent non-malignant congenital lesions reported in the reproductive system of young female foals and occasionally manifest as clinical findings at a later age ( 6 – 8 , 10 , 11 ). Teratomas are non-malignant neoplasms composed of the derivates of at least two of the embryonic layers: endoderm, mesoderm, and ectoderm (including neuroectoderm), exhibiting varying levels of maturation.…”

Section: Introductionmentioning

confidence: 99%

Case report: Findings in ovaries development from an aborted equine fetus

Cuccato,

Bertuglia,

Divari

et al. 2024

Front. Vet. Sci.

View full text Add to dashboard Cite

An aborted female foal was submitted for necropsy. During the gross examination, the ovaries were pale, grayish, and enlarged (6 × 5 cm), with a well-developed vascular structure surrounding the external surface; the cut surface of the ovaries showed a brownish parenchyma with white follicular areas mainly localized in the peripheral region. The ovaries were fixed for histological investigations. The histological evaluation of the ovaries showed polygonal-shaped cells with abundant cytoplasm and round or oval nuclei, arranged in cords of single cells. The tissue architecture was characterized by the presence of lobular-like tissues with a central vein. The tissue mimicking hepatocytes was delimited by a mature fibrous tissue and was surrounded by the normal ovarian tissue characterized by germinal epithelium and primordial follicular structures. Based on the histological findings, a diagnosis of bilateral ovarian hamartoma was carried out initially. For a better characterization of the ovarian tissue, the expression of tissue-specific (liver and ovary) markers was investigated using immunohistochemistry. Following the immunohistochemical analysis, the hamartoma diagnosis was excluded. The ovaries exhibited unique characteristics different from those of adult horse ovaries as well as unique morphological features different from other mammalian species. This case report enhances our understanding of ovaries at a later stage of pregnancy and unveils unique characteristics of horse ovaries development, avoiding misdiagnosis with pathological findings, hamartomas, or neoplasia.

show abstract

“…Although uncommon, ovarian teratomas that are classified into a category of the germ cell tumors have been previously described in human beings (Kraus, 1977;Outwater et al, 2001;Kuno et al, 2004;Schanmughapriya et al, 2011), nonhuman primates (Baskin et al, 1982), experimental rats (Tsubota et al, 2004), and domestic animals, including horses, pigs, dogs, and cattle (Dehner et al, 1970;Gruys et al, 1976;Rodríguez et al, 1994;Basaraba et al, 1998;MacLachlan and Kennedy, 2002;Sato et al, 2003;Lefebvre et al, 2005;Schlafer and Miller, 2007;Gamba et al, 2014). Spontaneous ovarian or intraabdominal teratomas have been reported in the avian species, including chickens (Campbell and Appleby, 1966;Helmboldt et al, 1974;Gupta, 1976;Mohamed et al, 2006), ducks (Cullen et al, 1991;Bolte and Burkhardt, 2000), a goose (Reece and Lister, 1993), and a bald eagle (Ford et al, 2006).…”

Section: Introductionmentioning

confidence: 99%

Ovarian teratoma displaying a wide variety of tissue components in a broiler chicken (<i>Gallus Domesticus</i>): morphological heterogeneity of pluripotential germ cell during tumorigenesis

Ohfuji¹

2016

Open Vet J.

View full text Add to dashboard Cite

Spontaneous ovarian teratoma was found in a seven-week-old female Chunky broiler chicken that was slaughtered for food. On post-mortem inspection, a spherical tumor mass attaching to a juvenile ovary was found in the abdominal cavity. Histopathologically, the tumor was comprised of immature mesenchymal stroma and a variety of mature tissue elements of mesodermal and ectodermal origin. In addition, there were multiple indistinguishable tissue elements, which showed no malignant cytological features but were unidentifiable as to corresponding embryological layer of origin. These heterogeneous teratoma tissues consisted of a variety of glandular, cystic, duct-like, and tubular structures, some of which exhibited a lining by a mixture of both keratinizing/non-keratinizing stratified squamous epithelial cells and cuboidal/columnar epithelial cells. The ovarian tetatoma was considered a benign and congenital one. The highly diverse differentiation of the teratoma might have manifested a morphological aspect of intrinsic character of the pluripotential germ cells during tumorigenesis.

show abstract

Ovarian teratoma in an equine fetus: a case report

Cited by 3 publications

References 9 publications

Equine ovarian teratomas: Diagnostic challenges illustrated by case reports

Equine ovarian teratomas: Diagnostic challenges illustrated by case reports

Case report: Findings in ovaries development from an aborted equine fetus

Ovarian teratoma displaying a wide variety of tissue components in a broiler chicken (<i>Gallus Domesticus</i>): morphological heterogeneity of pluripotential germ cell during tumorigenesis

Contact Info

Product

Resources

About