Heart Failure Care in Low- and Middle-Income Countries: A Systematic Review and Meta-Analysis

Callender, Thomas; Woodward, Mark; Roth, Gregory A.; Farzadfar, Farshad; Lemarié, J.; Gicquel, Stephanie; Atherton, J.; Rahimzadeh, Shadi; Ghaziani, Mehdi; Shaikh, Maaz; Bennett, Derrick; Patel, Anushka; Lam, Carolyn S.P.; Sliwa, Karen; Barretto, Antônio Carlos Pereira; Siswanto, Bambang Budi; Díaz, Alejandro; Herpin, D.; Krum, Henry; Eliasz, Thomas K; Forbes, Anna; Kiszely, Alastair; Khosla, Rajit; Petrinic, Tatjana; Praveen, Devarsetty; Shrivastava, Roohi; Du, Xin; MacMahon, Stephen; McMurray, John J.V.; Rahimi, Kazem

doi:10.1371/journal.pmed.1001699

Cited by 216 publications

(210 citation statements)

References 54 publications

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“…[4,5,8] Young hypertensive patients should be investigated for secondary causes of hypertension (Table 1). Standard anti-failure therapy and blood pressure control are the mainstays of therapy.…”

Section: Specific Aetiologies Of Hf Hypertensionmentioning

confidence: 99%

“…[3,4,8] Although IHD is considered uncommon among black Africans, there has been a notable rise in risk factors for atherosclerotic vascular disease in both urban and rural communities over the last few decades. [14] Patients presenting with ischaemic left ventricular dysfunction require rigorous risk factor management in addition to conventional HF therapy.…”

Section: Ischaemic Heart Diseasementioning

confidence: 99%

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Heart failure in sub-Saharan Africa: A clinical approach

et al. 2015

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Section: Specific Aetiologies Of Hf Hypertensionmentioning

confidence: 99%

Section: Ischaemic Heart Diseasementioning

confidence: 99%

Heart failure in sub-Saharan Africa: A clinical approach

et al. 2015

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“…Las características del síndrome de ICA pueden tener diferencias regionales significativas (9)(10)(11)(12)(13)(14) , por lo que es importante tomar conocimiento de la realidad local. Nuestro trabajo representa, hasta donde tenemos conocimiento, el primer registro de ICA en Perú y proporciona información inédita sobre esta importante patología cardiovascular.…”

Section: Discussionunclassified

“…Estas frecuencias son similares a lo reportado en registros de Estados Unidos y Europa (15)(16)(17) . Sin embargo, son diferentes a lo reportado en los registros latinoamericanos (9)(10)(11)(12)(13)(14) . Actualmente la enfermedad valvular continúa siendo una causa importante de hospitalización en nuestra imponen un pronóstico sombrío a los pacientes con ICA (3,18) ; en nuestro registro, casi la tercera parte de los pacientes tenían hospitalizaciones previas, con casi un 18% con tres o más hospitalizaciones, y un 23% con más de siete días de estancia hospitalaria.…”

Section: Discussionunclassified

Características clínico epidemiológicas de la insuficiencia cardíaca aguda en un hospital terciario de Lima, Perú

Pariona

Saldaña

Reyes

et al. 2017

Rev Peru Med Exp Salud Publica

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Con el objetivo de describir las características clínicas y epidemiológicas de la insuficiencia cardiaca aguda (ICA), se realizó un estudio descriptivo en 1075 pacientes de un hospital de Lima. La edad promedio fue 74 años y el 55% fueron de sexo masculino. El 39% tuvo ICA con fracción de eyección reducida, el 15% con fracción de eyección de rango medio y el 46% con fracción de eyección preservada. Las comorbilidades más frecuentes fueron la hipertensión arterial (52,6%) y la enfermedad coronaria (51%). El 29,2% de los pacientes tuvo hospitalizaciones previas por ICA. La mediana de la estancia hospitalaria fue de 3 días. La mortalidad intrahospitalaria por todas las causas fue 7,2%. La hospitalización ocurre, predominantemente, en pacientes de edad avanzada y con múltiples comorbilidades. El bajo uso de fármacos recomendados, conjuntamente con la alta frecuencia de hospitalizaciones previas, probablemente, inciden en la alta tasa de mortalidad registrada en el presente estudio.Palabras clave : Insuficiencia cardíaca, hospitalización, mortalidad intrahospitalaria, epidemiologia, Perú (fuente: DeCS BIREME) EPIDEMIOLOGICAL CLINICAL CHARACTERISTICS OF ACUTE CARDIAC INSUFFICIENCY IN A TERTIARY HOSPITAL IN LIMA, PERU ABSTRACTThe objective of this study was to describe the clinical and epidemiological characteristics of acute heart failure (AHF) in 1,075 patients from a hospital in Lima, Peru. The average patient age was 74 years and 55% of study subjects were men. Moreover, 39% of patients in the sample had AHF with low ejection fraction, 15% had intermediate ejection fraction, and 46% had preserved ejection fraction. The most common comorbidities were hypertension (52.6%) and coronary disease (51%). Moreover, 29.2% of patients had previous hospitalizations due to AHF. The median hospital stay was 3 days. The rate of inhospital mortality from all causes was 7.2%. Hospitalization was more common in elderly patients with multiple comorbidities. The low use of prescription drugs together with the high rate of previous hospitalizations may explain the high mortality rate reported in this study. INTRODUCCIÓNSe estima que aproximadamente un millón de hospitalizaciones por insuficiencia cardíaca aguda (ICA) se producen anualmente en los Estados Unidos y se espera que este número se eleve significativamente durante las próximas décadas (1)(2) . La ICA se ha convertido en la principal causa de hospitalización en personas mayores de 65 años, con altas tasas de mortalidad y reingresos frecuentes (3) . Es importante señalar que el costo del tratamiento por ICA está representado, principalmente, por el costo de las hospitalizaciones (4) . Aunque no existe una definición y/o nomenclatura universalmente aceptada para los "síndromes de insuficiencia cardíaca" que requieren hospitalización, probablemente la más aceptada es la preconizada por la Sociedad Europea de Cardiología: «Condición médica que amenaza la vida, que requiere típicamente hospitalización, caracterizada por un inicio rápido o empeoramiento de síntomas y/o signos ...

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“…In addition, there are >1 million admissions for HF annually in both the USA and Europe, accounting for the vast majority spent each year on HF‐related care 13, 14, 16. However, the socio‐economic burden of HF is especially worrisome in the low‐ and middle‐income regions of Africa, South America, the Middle East, and Asia Pacific, where the prevalence of HF is rising rapidly and the clinical characteristics, treatment patterns, and outcomes vary substantially 12, 17, 18, 19, 20, 21, 22, 23…”

Section: Introductionmentioning

confidence: 99%

International REgistry to assess medical Practice with lOngitudinal obseRvation for Treatment of Heart Failure (REPORT‐HF): rationale for and design of a global registry

Filippatos

Khan

Ambrosy

et al. 2015

European J of Heart Fail

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AimsThe clinical characteristics, initial presentation, management, and outcomes of patients hospitalized with new‐onset (first diagnosis) heart failure (HF) or decompensation of chronic HF are poorly understood worldwide. REPORT‐HF (International REgistry to assess medical Practice with lOngitudinal obseRvation for Treatment of Heart Failure) is a global, prospective, and observational study designed to characterize patient trajectories longitudinally during and following an index hospitalization for HF.MethodsData collection for the registry will be conducted at ∼300 sites located in ∼40 countries. Comprehensive data including demographics, clinical presentation, co‐morbidities, treatment patterns, quality of life, in‐hospital and post‐discharge outcomes, and health utilization and costs will be collected. Enrolment of ∼20 000 adult patients hospitalized with new‐onset (first diagnosis) HF or decompensation of chronic HF over a 3‐year period is planned with subsequent 3 years follow‐up.PerspectiveThe REPORT‐HF registry will explore the clinical characteristics, management, and outcomes of HF worldwide. This global research programme may have implications for the formulation of public health policy and the design and conduct of international clinical trials.

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Heart Failure Care in Low- and Middle-Income Countries: A Systematic Review and Meta-Analysis

Abstract: In a systematic review and meta-analysis, Kazem Rahimi and colleagues examine the burden of heart failure in low- and middle-income countries. Please see later in the article for the Editors' Summary

Cited by 216 publications

References 54 publications

Heart failure in sub-Saharan Africa: A clinical approach

Heart failure in sub-Saharan Africa: A clinical approach

Características clínico epidemiológicas de la insuficiencia cardíaca aguda en un hospital terciario de Lima, Perú

International REgistry to assess medical Practice with lOngitudinal obseRvation for Treatment of Heart Failure (REPORT‐HF): rationale for and design of a global registry

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