International REgistry to assess medical Practice with lOngitudinal obseRvation for Treatment of Heart Failure (REPORT‐HF): rationale for and design of a global registry

Abstract

AimsThe clinical characteristics, initial presentation, management, and outcomes of patients hospitalized with new‐onset (first diagnosis) heart failure (HF) or decompensation of chronic HF are poorly understood worldwide. REPORT‐HF (International REgistry to assess medical Practice with lOngitudinal obseRvation for Treatment of Heart Failure) is a global, prospective, and observational study designed to characterize patient trajectories longitudinally during and following an index hospitalization for HF.MethodsData collection for the registry will be conducted at ∼300 sites located in ∼40 countries. Comprehensive data including demographics, clinical presentation, co‐morbidities, treatment patterns, quality of life, in‐hospital and post‐discharge outcomes, and health utilization and costs will be collected. Enrolment of ∼20 000 adult patients hospitalized with new‐onset (first diagnosis) HF or decompensation of chronic HF over a 3‐year period is planned with subsequent 3 years follow‐up.PerspectiveThe REPORT‐HF registry will explore the clinical characteristics, management, and outcomes of HF worldwide. This global research programme may have implications for the formulation of public health policy and the design and conduct of international clinical trials.

Stem cell therapy for heart failure: Ensuring regenerative proficiency

“…Beyond validity, the utility of newest regenerative options will inform adoption reflecting real-world experience with emerging treatments poised to address unmet needs of broader populations [72,73]. Modern clinical development algorithms of candidate technology incorporate multi-disciplinary assessment by healthcare providers, developers, regulators, and payers [74] and seek active patient engagement [75].…”

About the RICA registry in patients with heart failure

“…We have read with great interest the article of Filippatos et al 1 about the rational and design of a new registry in heart failure, called International Registry to asses medical Practice with longitudinal observation for treatment of heart failure (REPORT-HF). In this article, authors cite several national and international registries, emphasizing the limitations of these previous observational studies and justifying the need of a new registry that collects information regarding long-term disease progression, including transition from acute to chronic situation.…”

May 2015 at a glance

“…Thus, both the in‐hospital phase and the transition to the outpatient setting and long‐term follow‐up will be assessed in this study, which is probably going to be the largest registry on HF including patients from all continents. Its rationale and design are published in the current issue of our journal …”