Influence of skin colour on diagnostic accuracy of the jaundice meter JM 103 in newborns

Samiee-Zafarghandy, Samira; Feberova, Jana; Williams, Kathryn; Yasseen, Abdool S.; Perkins, Sherry L.; Lemyre, Brigitte

doi:10.1136/archdischild-2013-305699

Cited by 36 publications

(20 citation statements)

References 24 publications

(10 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A noninvasive alternative is the determination of transcutaneous bilirubin (TCB). The new transcutaneous bilirubinometers use multiwavelength spectral reflectance to measure the optical density of cutaneous bilirubin and present greater precision than former devices [1]. Over the years, a close correlation has been demonstrated between TCB and serum bilirubin (TSB), the first is being currently used as a screening method for suspected neonatal jaundice [2].…”

Section: Introductionmentioning

confidence: 99%

Accuracy of transcutaneous bilirubin on covered skin in preterm and term newborns receiving phototherapy using a JM-105 bilirubinometer

et al. 2019

View full text Add to dashboard Cite

Objective Determine the suitability of transcutaneous bilirubin (TCB) as a tool to assess the effectiveness of phototherapy on patched skin. Study design A prospective observational study was conducted. We covered a fragment of skin (sternum) with a photoopaque patch. Several simultaneous TCB and TSB measurements were performed with the JM-105 bilirubinometer. Bland and Altman test evaluated the agreement between bilirubin levels. Result A total of 217 patients were studied, 48.8% were preterm. The mean difference between TSB and TCB before the start of treatment was 1.07 mg/dL. During phototherapy, differences on covered skin were 0.52, 0.27, and 0.39 mg/dL at 24, 48, and 72 h of therapy respectively. The best correlation was observed at 48 h in preterm infants. Conclusion The measurement of TCB on patched skin (PTCB) is useful for monitoring the response to phototherapy in term and preterm infants. We use a patch with a removable flap that eases successive measures without disturbing the patients.

show abstract

Section: Introductionmentioning

confidence: 99%

Accuracy of transcutaneous bilirubin on covered skin in preterm and term newborns receiving phototherapy using a JM-105 bilirubinometer

et al. 2019

View full text Add to dashboard Cite

show abstract

“…However, TcB may underestimate high SBR and, as they assess extravascular bilirubin, are unreliable if the neonate has received phototherapy treatment 13– 15 . The need for postnatal age- and ethnicity-specific nomograms further complicate TcB use 16, 17 .…”

Section: Introductionmentioning

confidence: 99%

Laboratory validation and field usability assessment of a point-of-care test for serum bilirubin levels in neonates in a tropical setting

Thielemans¹,

Hashmi²,

Priscilla³

et al. 2018

Wellcome Open Res

View full text Add to dashboard Cite

Background: Screening and monitoring serum bilirubin (SBR) in neonates is crucial to prevent neonatal hyperbilirubinemia (NH)-associated morbidity and mortality worldwide. A lack of resources is often a barrier for measuring SBR in developing countries. Reliable, cost-effective, easy to use point-of-care (POC) SBR tests are needed. This study aimed to evaluate the technical accuracy and usability of the Bilistick System (BS), a new bilirubin POC test, in a tropical setting. Methods: This was a mixed-methods study, including laboratory validation of the BS, direct observation of technical procedures as performed by the midwives and midwives’ assessment of the device’s easiness of use through focus group discussions (FGD) and a self-administered questionnaire. The study was conducted in a field clinic of the Shoklo Malaria Research Unit along the Thailand-Myanmar border between January and December 2017. Results: A total of 173 samples were tested at a median age of 4 days. BS generated an error message—providing no SBR readout—in 48.6% of the tests performed. For the tests that yielded a result, the correlation coefficient (95% CI) between BS and routine laboratory bilirubinometer SBR was 0.87 (0.77-0.93). The accuracy decreased with increasing haematocrit and at higher humidity (≥75%). Direct observation of the operators using the device and analysis of the focus group discussions and questionnaires indicated that the BS was considered easy to use and required limited training. Conclusions: This evaluation showed that the BS, in its current formulation, does not provide reliable results for measuring SBR in a tropical, low-resource setting but has acceptable usability features.

show abstract

“…Pearson correlation was found to be high in all the groups (r>0.9), though there was a trend for TCB to overestimate total serum bilirubin in non-caucasian babies and in babies >34 weeks [14]. In a study conducted by Samiee to study the influence of skin colour on diagnostic accuracy of the jaundice meter in 451 infants, also found a high association between TCB and Total serum bilirubin for all skin colours, though TCB was underestimating TSB in light and medium skin colours and overestimating in dark skin coloured babies [15].…”

Section: Discussionmentioning

confidence: 96%

Accuracy of transcutaneous bilirubinometer in assessing jaundice in newborns in Indian context

Gulvadi

Ramaraj

2017

Int J Pediatr Res

View full text Add to dashboard Cite

Background: Jaundice is a very common problem in newborns. Though measuring serum bilirubin is considered the gold standard method for estimating jaundice, Transcutaneous Bilirubin (TCB) measurement by TCB meter is now used in various centers. The accuracy of TCB meter is affected by many factors, skin colour being one of them. Aim: To analyze the accuracy of TCB meter in comparison to serum bilirubin for assessing jaundice in babies with different skin colours, in a tertiary care centre in South India. Methods: The study was performed in 200 babies in a medical college, in South India over a period of five months from august 2016 to December 2016. Term babies upto 7 th post natal day without any complications were analyzed. Babies were categorized based on their skin colour into 6 groups using the Fitz Patrick's colour scale. Jaundice was quantified in these babies by TCB meter and by measuring serum bilirubin at the same time and the values were compared. Results: Out of 200 babies, 6 babies were in group 2, 100 in group 3, 83 in group 4 and 11 in group 5. Though the Pearson correlation was linear in all the groups, it was lesser in the dark skinned babies. So we concluded that assessment of jaundice by TCB meter is not accurate in dark skinned babies. Hence serum bilirubin must be done in these babies before intervention. Conclusion: TCB is not accurate in assessing jaundice in dark skinned babies. Still it can be used as a valid screening tool.

show abstract

Influence of skin colour on diagnostic accuracy of the jaundice meter JM 103 in newborns

Abstract: The JM 103 is a useful screening tool to identify infants in need of serum bilirubin, regardless of skin colour. The effect of skin colour on the accuracy of this device at high levels of serum bilirubin could not be assessed fully due to small numbers in the light and dark groups.

Cited by 36 publications

References 24 publications

Accuracy of transcutaneous bilirubin on covered skin in preterm and term newborns receiving phototherapy using a JM-105 bilirubinometer

Accuracy of transcutaneous bilirubin on covered skin in preterm and term newborns receiving phototherapy using a JM-105 bilirubinometer

Laboratory validation and field usability assessment of a point-of-care test for serum bilirubin levels in neonates in a tropical setting

Accuracy of transcutaneous bilirubinometer in assessing jaundice in newborns in Indian context

Contact Info

Product

Resources

About