Enhanced electrocatalytic oxidation of isoniazid at electrochemically modified rhodium electrode for biological and pharmaceutical analysis

Electrochemical sensor for Isoniazid based on the glassy carbon electrode modified with reduced graphene oxide–Au nanomaterials

“…Among these methods, electrochemical methods offer advantages including high sensitivity, simplicity and reproducibility [15,[21][22][23][24][25][26][27]. Various types of electrodes have been developed to determine INZ, including overoxidized polypyrrole glassy carbon modified electrode [28], poly(sulfosalicylic acid)/electroreduced carboxylated graphene modified glassy carbon electrode [19], carbon nanotube modified electrode [25], bentonite clay modified electrodes [21], poly(amidosulfonic acid) modified glassy carbon electrode [27], rhodium modified glassy carbon electrode [15], ordered mesoporous carbon modified GCE [26], poly(L-histidine) modified screen-printed carbon electrode [22], gold electrode [29], dropping mercury electrode [30], electrochemically reduced graphene oxide modified GCE [16] and thionine immobilized multiwalled carbon nanotube modified carbon paste electrode [31]. But, in most papers, the oxidation of INZ at modified electrodes required a high over-potential, acidic or alkaline supporting electrolyte, which brought great inconvenience to the analytical procedure and unsuitable for the detection [26].…”

“…A safe, reliable and economical method has to be made to detect the concentration of these drugs simultaneously either in pure form, in pharmaceutical preparations or in biological fluids. At present, various methods have been developed for the determination of INZ, such as high-performance liquid chromatography [2][3][4][5], gas chromatography [6], capillary electrophoresis [7], chemiluminescence [8,9], localized surface plasmon resonance [10], ultraviolet-visible spectrophotometry [11,12], fluorimetry [13] and electrochemical methods [14][15][16][17][18][19][20]. Among these methods, electrochemical methods offer advantages including high sensitivity, simplicity and reproducibility [15,[21][22][23][24][25][26][27].…”

“…At present, various methods have been developed for the determination of INZ, such as high-performance liquid chromatography [2][3][4][5], gas chromatography [6], capillary electrophoresis [7], chemiluminescence [8,9], localized surface plasmon resonance [10], ultraviolet-visible spectrophotometry [11,12], fluorimetry [13] and electrochemical methods [14][15][16][17][18][19][20]. Among these methods, electrochemical methods offer advantages including high sensitivity, simplicity and reproducibility [15,[21][22][23][24][25][26][27]. Various types of electrodes have been developed to determine INZ, including overoxidized polypyrrole glassy carbon modified electrode [28], poly(sulfosalicylic acid)/electroreduced carboxylated graphene modified glassy carbon electrode [19], carbon nanotube modified electrode [25], bentonite clay modified electrodes [21], poly(amidosulfonic acid) modified glassy carbon electrode [27], rhodium modified glassy carbon electrode [15], ordered mesoporous carbon modified GCE [26], poly(L-histidine) modified screen-printed carbon electrode [22], gold electrode [29], dropping mercury electrode [30], electrochemically reduced graphene oxide modified GCE [16] and thionine immobilized multiwalled carbon nanotube modified carbon paste electrode [31].…”

Silver Hexacyanoferrate (III) on a Hybrid Graphene Oxide/PAMAM Dendrimer Surface and Application as an Electrocatalyst in the Detection of Isoniazid

“…Table presents a comparison of similar studies carried out in the literature for Isoniazid detection. These results indicate the analytical benefits obtained by applying the GOPAgH modified graphite paste electrode, which presented a better LOD when compared to other studies.…”

Development of a Nafion/MWCNT-SPCE-Based Portable Sensor for the Voltammetric Analysis of the Anti-Tuberculosis Drug Ethambutol

“…In this context, there is a strong need for extensive analysis of anti-TB drugs, being essential to design and develop a portable, sensitive and reliable sensor for antimycobacterium drugs control [ 6 ]. Notwithstanding the existence of several analytical methods for the detection of anti-TB drugs, such as high performance liquid chromatography (HPLC) [ 7 ], liquid chromatography/tandem mass spectrometry (LC/MS) [ 8 , 9 , 10 ], micellar electrokinetic capillary chromatography (MEKC) [ 11 ], chemiluminescence [ 12 , 13 , 14 ], fluorimetry [ 15 , 16 ], colorimetry [ 17 ], titrimetry [ 18 ] and voltammetry [ 19 , 20 ], there is still a strong need for the development of portable devices for effective and rapid analysis of these compounds. Among the reported methods, electrochemical detection is recognized as one of the most promising analytical techniques due to its simplicity, cost-effectiveness and potential for in-situ drug monitoring [ 6 , 21 ].…”