2,4,6-Trinitrophenyl 3-bromobenzoate

Abstract

In the title picryl-substituted ester, C13H6BrN3O8, the mean plane of the central ester C–O–C(=O)–C fragment (r.m.s. deviation= 0.0186 Å) is rotated by 84.73 (7)° and 19.92 (12)° to the picryl and phenyl rings, respectively. In the crystal, the mol­ecules are linked by C—H⋯O inter­actions, forming centrosymmetric dimers enclosing R 2 2(10) and R 2 2(22) ring motifs along [001] and further helical chains of dimers enclosing R 2 2(10) ring motifs along [010].

(5-Chloroquinolin-8-yl)-2-fluorobenzoate. The Halogen Bond as a Structure Director

“…The incorporation of diverse halogen atoms into their structures, especially chlorine and fluorine, can lead to important changes in their chemical, pharmacological and physical properties [8][9][10]. In this sense, and continuing with our current studies on the structural properties of novel aryl and heteroaryl benzoates of synthetic and biological interest [11][12][13][14][15], the fluoroquinoline-derivative 3 was obtained by a direct reaction of 2-fluorobenzoyl chloride 1 and 5-chloro-8-hydroxyquinoline 2 in the presence of triethylamine as base (Scheme 1). Scheme 1.…”