The fetal outcomes of pregnancies of systemic lupus erythematosus patients in northern Israel

Abstract

The pregnancy outcomes of our cohort are similar to those previously published, worse than the general population. Ethnicity did not affect the fetal outcome.

The study of factors associated with pregnancy outcomes in patients with systemic lupus erythematosus

“…The results of the present study demonstrate that high levels of CRP, APS positivity, anti-dsDNA positivity and renal involvement are predictors of adverse pregnancy outcomes in SLE patients. These data are in consistent with previous findings [16,[18][19][20]. The age of SLE onset was impressed the pregnancy complications in our assessment in contrast with the report of Feld et al [19].…”

“…This conferred approximately a 5.2-fold increased risk of unfavorable outcomes (OR: 5.18, 95% CI 1.681-13.647, P = 0.001) when compared to APS-negative patients. Fled et al also have reported that APS is associated with an odds ratio of 5.31 [19].…”

A comprehensive review of the clinical approach to pregnancy and systemic lupus erythematosus

“…Active/flaring SLE at conception or in the 4e6 months before has also been associated with adverse pregnancy outcomes (APO) other than EPL: late pregnancy losses (LPL), neonatal death, preterm delivery/prematurity, hypertensive complications and probably intrauterine growth restriction (IUGR) and small for gestational age (SGA) newborns [16,22e27]. Even though the disease could be in remission at the time of conception, major organ involvements such as renal or neurological, should be considered as risk factors for APO [13,21,28,29].…”