The use of glyburide in the management of gestational diabetes mellitus: A meta-analysis

Zeng, Yonglian; Li, Mujun; Chen, Yue; Jiang, Li; Wang, Sumei; Mo, Xiaoliang; Li, Bin-yi

doi:10.1016/j.advms.2014.03.001

Cited by 56 publications

(53 citation statements)

References 37 publications

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“…Several recent meta-analyses have also looked at outcomes in women treated with glyburide compared with insulin 80838485. The meta-analysis by Balsells et al found that women treated with glyburide had higher birthweight infants, more macrosomia, and more neonatal hypoglycemia than those treated with insulin 57.…”

Section: Glyburidementioning

confidence: 99%

Novel therapies for diabetes mellitus in pregnancy

Feghali

Scifres

2018

BMJ

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Diabetes is a common complication of pregnancy, and the prevalence of all types of the disease is increasing worldwide. Diabetes in pregnancy is associated with short term and long term adverse effects for mother and child. The goal of treatment of diabetes in pregnancy is to minimize maternal and fetal adverse events related to hyperglycemia. Treatment options vary by type of diabetes, from a focus on lifestyle modifications in gestational diabetes to continuous glucose monitoring and insulin pumps in pregestational diabetes. Nevertheless, given the commonality of hyperglycemia, considerable overlap exists in the treatment of different types of diabetes in pregnancy. Also, despite ongoing research on treatment of diabetes in pregnancy for decades, changes in the characteristics of the patient population have highlighted the limited effectiveness of different therapies. Specifically, despite the co-occurrence of obesity and diabetes, treatment recommendations including glycemic targets are not altered in such cases and a single optimal treatment strategy for each type of diabetes in pregnancy does not seem to exist. Rather, the approach to treating pregnant women with diabetes likely needs to be individualized to maximize the short term and long term health of mother and child. This article will review recent clinical studies to summarize established treatment strategies and introduce novel therapies for diabetes in pregnancy.

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Section: Glyburidementioning

confidence: 99%

Novel therapies for diabetes mellitus in pregnancy

Feghali

Scifres

2018

BMJ

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“…The analysis included seven trials that compared glyburide with insulin and demonstrated that glyburide was associated with a higher birth weight, an almost threefold higher risk of macrosomia, and a twofold higher risk of neonatal hypoglycemia . The findings of Balsells et al are comparable with those of an earlier meta‐analysis conducted by Zeng et al However, this earlier study concluded that glyburide is as effective as insulin, while also reporting a higher risk of neonatal hypoglycemia, high birth weight, and macrosomia …”

Section: Treatmentmentioning

confidence: 82%

Gestational Diabetes Mellitus:current knowledge and unmet needs

Koning

Hoogenberg

Lutgers

et al. 2016

Journal of Diabetes

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Gestational diabetes mellitus (GDM) is a global health concern, not only because its prevalence is high and on the increase, but also because of the potential implications for the health of mothers and their offspring. Unfortunately, there is considerable controversy in the literature surrounding the diagnosis and treatment of GDM, as well as the possible long‐term consequences for the offspring. As a result, worldwide there is a lack of uniformly accepted diagnostic criteria and the advice regarding the treatment of GDM, including diet, insulin therapy, and the use of oral blood glucose‐lowering agents, is highly variable. In this review we provide an overview of the important issues in the field of GDM, including diagnostic criteria, different treatment regimens available, and the long‐term consequences of GDM in the offspring.

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“…Eğer bu dozlarda glisemik hedeflere ulaşıla-mazsa, tedaviye bazal insülin eklenmesi ya da oral ajan kesilerek insülin tedavisine başlanması gerekir (60,61). Son dönemde yapılan bir metaanalizde, gliburid ile neonatal hipoglisemi ve makrozomi risklerinin insüline göre daha fazla olduğu saptanmıştır (62).…”

Section: Gliburidunclassified

Gestational diabetes mellitus

Öztürk¹

2015

Sisli Etfal

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The use of glyburide in the management of gestational diabetes mellitus: A meta-analysis

Cited by 56 publications

References 37 publications

Novel therapies for diabetes mellitus in pregnancy

Novel therapies for diabetes mellitus in pregnancy

Gestational Diabetes Mellitus:current knowledge and unmet needs

Gestational diabetes mellitus

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