“…"Save a minute -save a day" model is an example of a complex OR/MS model in stroke care systems domain. Various OR/MS models addressing a number of interventions in stroke care systems have been proposed by OR/MS researchers and practitioners ( Churilov & Donnan, 2012 ).These applications target, in particular, the areas of stroke care operations improvement ( Bayer, Petsoulas, Cox, Honeyman, & Barlow, 2010;Churilov et al, 2013;Cordeaux, Hughes, & Elder, 2011;Mar, Arrospide, & Comas, 2010;Pitt et al, 2012 ), economic analysis ( Bayer et al, 2010;Davidson, Husberg, Janzon, Oldgren, & Levin, 2013;Ghijben, Lancsar, & Zavarsek, 2014;Mar et al, 2010 ), public policy ( Bayer et al, 2010;Churilov et al, 2013;Davidson, et al, 2013;Ghijben et al, 2014;Monks, Pitt, Stein, & James, 2014;Yang, Chen, Chitkara, & Xu, 2014 ), and clinical decision making ( Ghijben et al, 2014;Mar et al, 2010;Monks et al, 2012;Pitt et al, 2012;Yang et al, 2014 ).…”