TBS result is not affected by lumbar spine osteoarthritis

Kolta, Sami; Briot, Karine; Fechtenbaum, J.; Paternotte, Simon; Armbrecht, Gabriele; Felsenberg, Dieter; Glüer, Claus C.; Eastell, Richard; Roux, Christian

doi:10.1007/s00198-014-2685-6

Cited by 98 publications

(54 citation statements)

References 28 publications

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“…Finally, although there are studies suggesting that OA does not affect LS TBS (44,70), there are no data showing that TBS is useful to assess fracture risk in patients with OA and additional research is needed.…”

Section: Discussionmentioning

confidence: 92%

See 1 more Smart Citation

Fracture Risk Prediction by Non-BMD DXA Measures: the 2015 ISCD Official Positions Part 2: Trabecular Bone Score

Silva

Broy

Boutroy

et al. 2015

Journal of Clinical Densitometry

289

193

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Section: Discussionmentioning

confidence: 92%

“…Previous studies have suggested that TBS is not affected by osteoarthritic changes of the LS (44,70). In the study of Dufour et al (44), designed to evaluate age-related changes in TBS in a cohort of Caucasian French women, the influence of LS osteoarthritis (OA) on TBS was explored in a subgroup of 390 subjects (50e88.5 yr).…”

Section: Osteoarthritismentioning

confidence: 99%

Fracture Risk Prediction by Non-BMD DXA Measures: the 2015 ISCD Official Positions Part 2: Trabecular Bone Score

Silva

Broy

Boutroy

et al. 2015

Journal of Clinical Densitometry

289

193

View full text Add to dashboard Cite

“…Recent studies have suggested that TBS may be less affected by such artefactual influences [79]. Both points were demonstrated in a recent study by Kolta et al [80] in which 1254 postmenopausal women in the European OPUS cohort, mean age 67 years, underwent TBS measurement at baseline and again at a mean of six years later. The severity of spinal osteoarthritis was graded according to Kellgren and Lawrence [81].…”

Section: Osteoarthritismentioning

confidence: 86%

Trabecular bone score (TBS) as a new complementary approach for osteoporosis evaluation in clinical practice

Harvey

Glüer

Binkley

et al. 2015

Bone

386

255

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Trabecular bone score (TBS) is a recently-developed analytical tool that performs novel grey-level texture measurements on lumbar spine dual X-ray absorptiometry (DXA) images, and thereby captures information relating to trabecular microarchitecture. In order for TBS to usefully add to bone mineral density (BMD) and clinical risk factors in osteoporosis risk stratification, it must be independently associated with fracture risk, readily obtainable, and ideally, present a risk which is amenable to osteoporosis treatment. This paper summarizes a review of the scientific literature performed by a Working Group of the European Society for Clinical and Economic Aspects of Osteoporosis and Osteoarthritis. Low TBS is consistently associated with an increase in both prevalent and incident fractures that is partly independent of both clinical risk factors and areal BMD (aBMD) at the lumbar spine and proximal femur. More recently, TBS has been shown to have predictive value for fracture independent of fracture probabilities using the FRAX ® algorithm. Although TBS changes with osteoporosis treatment, the magnitude is less than that of aBMD of the spine, and it is not clear how change in TBS relates to fracture risk reduction. TBS (corresponding author post-publication: nch@mrc.soton.ac.uk. (corresponding author pre-publication: w.j.pontefract@sheffield.ac.uk). Europe PMC Funders Group Europe PMC Funders Author ManuscriptsEurope PMC Funders Author Manuscripts may also have a role in the assessment of fracture risk in some causes of secondary osteoporosis (e.g. diabetes, hyperparathyroidism and glucocorticoid-induced osteoporosis). In conclusion, there is a role for TBS in fracture risk assessment in combination with both aBMD and FRAX.

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“…Unlike aBMD, TBS is not affected by osteoarthritis. 11 It can be calculated retrospectively, allowing the estimation of bone texture from a previously acquired DXA scan.…”

Section: Introductionmentioning

confidence: 99%

Trabecular bone score in healthy ageing

Bazzocchi¹,

Ponti²,

Diano³

et al. 2015

BJR

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TBS result is not affected by lumbar spine osteoarthritis

Abstract: In postmenopausal women, lumbar osteoarthritis leads to an increase in lumbar spine aBMD. In contrast, spine TBS is not affected by lumbar osteoarthritis.

Cited by 98 publications

References 28 publications

Fracture Risk Prediction by Non-BMD DXA Measures: the 2015 ISCD Official Positions Part 2: Trabecular Bone Score

Fracture Risk Prediction by Non-BMD DXA Measures: the 2015 ISCD Official Positions Part 2: Trabecular Bone Score

Trabecular bone score (TBS) as a new complementary approach for osteoporosis evaluation in clinical practice

Trabecular bone score in healthy ageing

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