Polyphenols pattern and correlation with antioxidant activities of berries extracts from four different populations of Sicilian<i>Sambucus nigra</i>L.

Mandrone, Manuela; Lorenzi, Beatrice; Maggio, Antonella; Mantia, Tommaso La; Scordino, Monica; Bruno, Maurizio; Poli, Ferruccio

doi:10.1080/14786419.2014.898147

Cited by 24 publications

(25 citation statements)

References 32 publications

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“…Total phenolic content of Sambucus nigra fruit is 6831.1 mg gallic acid equivalent (GAE) per kg (extracted with 3% acidified methanol) (Mikulic-Petkovsek et al, 2016), which is in accordance with other reports 6399 mg gallic acid equivalent (GAE) per kg by (Duymus et al, 2014) and also (Akbulut et al, 2009;Jungmin and Finn, 2007;Mandrone et al, 2014).…”

Section: Sugars Composition Of Sambucus Nigra L Fruits Flowers and supporting

confidence: 83%

Chemical Profiles and Antioxidant Activity of Black Elder (Sambucus Nigra L.) - A Review

Petruţ¹,

Muste²,

Mureşan³

et al. 2017

BUASVMCN-FST

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All plant parts of black elder (leaves, berries, inflorescences, roots, shoots, bark) have a long history of use in herbal remedy or lots of culinary uses, widespread in almost every continent of the world. Pro-health properties indicated a role of black elderberry products intake in the prevention of cancer and diabetes. This paper presents an overview of the evaluation of biochemical compounds (sugars, organic acids, total phenolics, antioxidative activity, flavonoids, flavor and volatile compounds), found in flowers, berries and leaves of Sambucus nigra L. The variability of concentration compounds are found by uniform maturity of each phenophase of black elder, hence the need varieties improve the quantity and quality of its yield. Black elder has food industry properties associated with the presence of increased nutritive and decreased caloric value at fruits best correlated with the content of sugars and organic acids of flower, organic acids as a important metabolic pathway of proteins, lipids, carbohydrates. Several studies have confirmed that Sambucus nigra L. is a valuable raw material with many nutrients and bioactive substances, being extraordinarily rich in antioxidants, and the leaves are remarked as easily available source of antioxidant preparations in different domains (food products, pharmaceutics, or cosmetics). A bush of Sambucus nigra L. in the garden is our true handy pharmacy, a food market like as functional ingredient, a spot of color with unmistakable smell.

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Section: Sugars Composition Of Sambucus Nigra L Fruits Flowers and supporting

confidence: 83%

Chemical Profiles and Antioxidant Activity of Black Elder (Sambucus Nigra L.) - A Review

Petruţ¹,

Muste²,

Mureşan³

et al. 2017

BUASVMCN-FST

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“…Cyanidin-3-glucoside and cyanidin-3-sambubioside were previously reported as the prevailing anthocyanins in elderberry. In Sicilian elderberry (from Italy) cyanidin-3glucoside was prevailing [30], whereas in our samples and in Austrian elderberry selection cyanidin-3-sambubioside was the major anthocyanin [17]. It is important to note that, in our analytical conditions, the two anthocyanins, even if they had similar retention time, could be sufficiently separated and quantified (Figure 1), whereas in other procedures they coeluted [17].…”

Section: Anthocyanins and Flavonols Extraction And Quantificationmentioning

confidence: 52%

Improvement of Analytical Methods for the Determination of Polyphenolic Bioactive Compounds in Berry Fruits

Caruso

Galgano

Pecora

et al. 2015

Journal of Chemistry

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Berry fruits contain high levels of different phytochemicals, most of which are phenolic molecules. Fruits of the same cultivar from different locations and different harvest years have different chemical compositions, particularly related to polyphenols. The difference may be due to specific climatic conditions, the type of soil in which the plants grow, and the stresses to which the plants were subjected because these phytochemicals are produced as a defense mechanism through a secondary metabolic process. For this reason, it is important to establish simple and reliable procedure to determine polyphenolic compounds in berry fruits considering the increasing attention on these compounds for different potential uses. In order to choose and to improve the most adequate analytical procedure for the determination of the polyphenolic substances in berry fruits, different methods were applied and compared on samples of elderberry and blackberry.

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“…In addition, phenolic acid constituents of S.ambucus FormosanaNakai, including caffeic acid, caffeotannic acid, chlorogenic acid, coumaric acid, ferulic acid, and gallic acid, have been identified as the members of the most important active components with anti-inflammatory, anti-tumor and anti-hepatotoxic activities (Chen et al, 2001;Liao et al, 2006;Yang and Lin, 2004;Zhang et al, 2010). Active components of Sambucus FormosanaNakai are similar to those of other Sambucus species, including Sambucus nigra L. and Sambucus lanceolata, which process antioxidant, antiradical, antiviral, antimicrobial, and anti-inflammatory activities (Barak et al, 2001;Krawitz et al, 2011;Mandrone et al, 2014;Pinto et al, 2017;Pliszka, 2017;Porter and Bode, 2017;Turek and Cisowski, 2007). Especially, the extract of Sambucus nigra L. exerts the antiviral activity against influenza A and B viruses, human immunodeficiency virus, and the herpes simplex virus type 1 (Krawitz et al, 2011;Serkedjieva et al, 1990;Zakay-Rones et al, 1995;Amoros et al, 1992;Mahmood et al, 1993;Roschek et al, 2009).…”

Section: Introductionmentioning

confidence: 93%

Antiviral activity of Sambucus FormosanaNakai ethanol extract and related phenolic acid constituents against human coronavirus NL63

et al. 2019

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Human coronavirus NL63 (HCoV-NL63), one of the main circulating HCoVs worldwide, causes respiratory tract illnesses like runny nose, cough, bronchiolitis and pneumonia. Recently, a severe respiratory illness outbreak of HCoV-NL63 has been reported in a long-term care facility. Sambucus FormosanaNakai, a species of elderberry, is a traditional medicinal herb with anti-inflammatory and antiviral potential. The study investigated the antiviral activity of Sambucus FormosanaNakai stem ethanol extract and some phenolic acid constituents against HCoV-NL63. The extract was less cytotoxic and concentration-dependently increased anti-HCoV-NL63 activities, including cytopathicity, sub-G1 fraction, virus yield (IC50 = 1.17 μg/ml), plaque formation (IC50 = 4.67 μg/ml) and virus attachment (IC50 = 15.75 μg/ml). Among the phenolic acid constituents in Sambucus FormosanaNakai extract, caffeic acid, chlorogenic acid and gallic acid sustained the anti-HCoV-NL63 activity that was ranked in the following order of virus yield reduction: caffeic acid (IC 50 = 3.54 μM) > chlorogenic acid (IC 50 = 43.45 μM) > coumaric acid (IC 50 = 71.48 μM). Caffeic acid significantly inhibited the replication of HCoV-NL63 in a cell-type independent manner, and specifically blocked virus attachment (IC 50 = 8.1 μM). Therefore, the results revealed that Sambucus Formosana Nakai stem ethanol extract displayed the strong anti-HCoV-NL63 potential; caffeic acid could be the vital component with anti-HCoV-NL63 activity. The finding could be helpful for developing antivirals against HCoV-NL63.

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Polyphenols pattern and correlation with antioxidant activities of berries extracts from four different populations of SicilianSambucus nigraL.

Cited by 24 publications

References 32 publications

Chemical Profiles and Antioxidant Activity of Black Elder (Sambucus Nigra L.) - A Review

Chemical Profiles and Antioxidant Activity of Black Elder (Sambucus Nigra L.) - A Review

Improvement of Analytical Methods for the Determination of Polyphenolic Bioactive Compounds in Berry Fruits

Antiviral activity of Sambucus FormosanaNakai ethanol extract and related phenolic acid constituents against human coronavirus NL63

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