Probiotics reduce psychological stress in patients before laryngeal cancer surgery

Abstract

Probiotics can ameliorate the clinical anxiety and biochemical features of stress in patients scheduled for laryngectomy.

Probiotic supplementation can positively affect anxiety and depressive symptoms: a systematic review of randomized controlled trials

“…However, the majority of included trials did not disclose their method of randomization sequence generation or whether they employed concealed allocation. All but two studies [37,39] provided information on use of double blinding and the use of placebos (of identical taste and appearance), while three studies failed to report group means and/or variance estimates [36][37][38].…”

“…Of these, 10 additional studies were eliminated in a second round, leaving a total of 10 RCTs remaining to be included the present review [33][34][35][36][37][38][39][40][41][42]. Of the 10 selected RCTs, six evaluated the effect of probiotic supplementation on anxiety and depressive symptoms in healthy adults [34,35,[38][39][40]42] while four evaluated anxiety and depressive symptoms in clinicallydiagnosed samples (e.g.…”

“…Bowel Syndrome, and Cancer) [33,36,37,41]. In total, six studies [34][35][36][40][41][42] included an assessment of both anxiety and depressive symptoms, while four [33,[37][38][39] evaluated either anxiety or depressive symptoms.…”

“…In total, six studies [34][35][36][40][41][42] included an assessment of both anxiety and depressive symptoms, while four [33,[37][38][39] evaluated either anxiety or depressive symptoms. In all but one study [37], the probiotic species administered were of Lactobacillus or Bifidobacterium strains in single [36,38] or multiple strain formulations [33][34][35]37,[39][40][41][42] (see Table 1 for specific strains). Six RCTs also reported assessments of relevant physiological indices along with assessments of anxiety and depressive symptoms,…”

“…including changes in stress biomarkers [34,35,37,40], GI microbiota [36], or immune parameters [39]. All assessments of mood were performed through self-report measures with established psychometric that are frequently referenced in the literature.…”