Molecular Assessment, Drug-Resistant Profile, and Spacer Oligonucleotide Typing (Spoligotyping) of<i>Mycobacterium tuberculosis</i>Strains From Tamaulipas, México

Bocanegra-García, Virgilio; Garza‐González, Elvira; Cruz-Pulido, Wendy Lizeth; Guevara-Molina, Yahaira Lizeth; Cantú-Ramírez, Rubén; González, Gloria M.; Rivera, Gildardo; Palma-Nicolás, José Prisco

doi:10.1002/jcla.21650

Cited by 10 publications

(3 citation statements)

References 28 publications

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“…And they were identified as the causative agents of tuberculosis in the world. For each families of MTB resistance to rifampicin, the prevalence was analyzed for the selected studies as follows: Beijing nineteen studies [14, 15, 16, 17, 18, 19, 20, 21, 22, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31], LAM ten studies [15, 17, 23, 25, 28, 29, 32, 33, 34, 35], T ten studies [3, 15, 16, 17, 23, 27, 28, 32, 34, 35], EAI eight studies [18, 22, 25, 27, 28, 29, 33, 36], Ural four studies [15, 17, 30, 34] Haarlem five studies [15, 23, 25, 28, 34], CAS four studies [15, 29, 30, 35] and MANU two studies [16, 29]. The proportion of rifampicin resistance varies by the type of regions and strains.…”

Section: Resultsmentioning

confidence: 99%

“…But using DNA sequencing for detecting mutations associated with resistance genes were 98.1% for isoniazid (95% CI, 94.4 to 99.6), and the specificity for all drugs was 99.6% (95% CI, 97.9 to 100) or greater [50]. Of twenty three included studies, three studies used both genotyping (detecting mutation in rpoB, katG, gyrA and rrs gene) and phenotypic (proportional method) drug susceptibility methods for detecting resistance isolates [28, 29, 32] ad five studies target drug resistance mutations in rpoB, katG [17, 21, 22, 51, 52], gyrA inhA and rrs gene for identifying drug resistance strain [17, 22, 52]. The remaining 15 studies relied on medium based proportional method.…”

Section: Discussionmentioning

confidence: 99%

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Resistance of Mycobacterium tuberculosis strains to Rifampicin: A systematic review and meta-analysis

Feyisa

Abdurahman

Jimma

et al. 2019

Heliyon

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IntroductionAntitubercular drug resistance strain is a horrifying barrier to effective TB treatment and prevention. The present study aimed to determine the prevalence and geographical distribution of rifampicin-resistance M. tuberculosis (MTB) strains.MethodsWe searched two electronic databases, PubMed and EMBASE, until 26 March 2017 and updated our search on 27 April 2018 and accessed all prevalence studies of MTB strain and their drug susceptibility patterns to rifampicin. The pooled prevalence estimate was determined using random effects model.ResultsWe identified 23 studies satisfying the inclusion criteria. The proportion of rifampicin resistance strains was diverged depending on the type of strains, country and Regions. The pooled estimate of rifampicin-resistance strains of MTB for the included studies was 4% (95% CI: 3–5%). In subgroup analysis based on World Health Organization (WHO) Regions, the pooled estimate of rifampicin-resistance strains of MTB was 11% (95% CI: 9–13%) with the Western Pacific Region 24%, Europian Region 10%, South-East Asian Region 6%, African Region 3% and Region of American 1%. Beijing family was the most dominant strain resistance to rifampicin with pooled prevalence of 14% (95% CI: 10–18%). The pooled prevalence of other families, i.e. EAI, T, CAS, MANU, Haarlem, LAM and Ural, was ≤2% for each.ConclusionHigh burden of rifampicin resistance MTB strains was identified in the Western Pacific Region. Of these, Beijing family was predominantly resistance to rifampicin in Western Pacific Region and South-East Asian Region and also spread to European Region and Region of American.

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Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Resistance of Mycobacterium tuberculosis strains to Rifampicin: A systematic review and meta-analysis

Feyisa

Abdurahman

Jimma

et al. 2019

Heliyon

View full text Add to dashboard Cite

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“…Despite this, whole-genome sequencing has revealed substantial genetic diversity between strains, leading to an improved phylogenetic SNP-based strain classification [28]. Studies in Peru [25,29,30], Argentina [31], Mexico [32,33], and Brazil [34,35,36,37] have all examined the genetic diversity of MTB in Latin America and have established that the predominant strains have evolved from the Euro-American lineage 4. This domination of lineage 4 in South America, alongside its worldwide distribution, supports the hypothesis that it was introduced and dispersed by European colonialists in the mid-sixteenth to nineteenth centuries, as discussed above [38,39,40,41].…”

Section: Discussionmentioning

confidence: 99%

Tuberculosis Genetic Epidemiology: A Latin American Perspective

Woodman

Haeusler

Grandjean

2019

Genes

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There are an estimated 10 million new cases of tuberculosis worldwide annually, with 282,000 new or relapsed cases each year reported from the Americas. With improvements in genome sequencing technology, it is now possible to study the genetic diversity of tuberculosis with much greater resolution. Although tuberculosis bacteria do not engage in horizontal gene transfer, the genome is far more variable than previously thought. The study of genome-wide variation in tuberculosis has improved our understanding of the evolutionary origins of tuberculosis, the arrival of tuberculosis in Latin America, the genetic determinants of drug resistance, and lineage-specific associations with important clinical phenotypes. This article reviews what is known about the arrival of tuberculosis in Latin America, the genetic diversity of tuberculosis in Latin America, and the genotypic determinants of clinical phenotypes.

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rpoB, katG and inhA mutations in multi-drug resistant strains of Mycobacterium tuberculosis clinical isolates from southeast Mexico

Zenteno-Cuevas

Cuevas-Córdoba

Parissi-Crivelli³

2019

Enfermedades Infecciosas y Microbiología Clínica

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Molecular Assessment, Drug-Resistant Profile, and Spacer Oligonucleotide Typing (Spoligotyping) ofMycobacterium tuberculosisStrains From Tamaulipas, México

Abstract: This and other studies report a high rate of orphan spoligotypes, which highlights the need for genotyping implementation as a routine technique for better understanding of M. tuberculosis strains in developing countries such as Mexico.

Cited by 10 publications

References 28 publications

Resistance of Mycobacterium tuberculosis strains to Rifampicin: A systematic review and meta-analysis

Resistance of Mycobacterium tuberculosis strains to Rifampicin: A systematic review and meta-analysis

Tuberculosis Genetic Epidemiology: A Latin American Perspective

rpoB, katG and inhA mutations in multi-drug resistant strains of Mycobacterium tuberculosis clinical isolates from southeast Mexico

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