2014
DOI: 10.1186/1472-6882-14-1
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Effects of Eleutheroside B and Eleutheroside E on activity of cytochrome P450 in rat liver microsomes

Abstract: BackgroundChemicals of herbal products may cause unexpected toxicity or adverse effect by the potential for alteration of the activity of CYP450 when co-administered with other drugs. Eleutherococcus senticosus (ES), has been widely used as a traditional herbal medicine and popular herbal dietary supplements, and often co-administered with many other drugs. The main bioactive constituents of ES were considered to be eleutherosides including eleutheroside B (EB) and eleutheroside E (EE). This study was to inves… Show more

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Cited by 262 publications
(198 citation statements)
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References 28 publications
(26 reference statements)
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“…Given the popularity of CHA, and evidence indicating CHA are primarily used to supplement rather than replace conventional health care (57), disclosure of CHA use to health-care providers is crucial for ensuring coordination of care (8), for minimizing any potential adverse reactions between CHA and conventional treatments (9, 10), and for improving adherence to treatment (e.g., 11). Disclosing CHA use can also facilitate better integration of CHA into both conventional care treatments and self-care.…”
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confidence: 99%
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“…Given the popularity of CHA, and evidence indicating CHA are primarily used to supplement rather than replace conventional health care (57), disclosure of CHA use to health-care providers is crucial for ensuring coordination of care (8), for minimizing any potential adverse reactions between CHA and conventional treatments (9, 10), and for improving adherence to treatment (e.g., 11). Disclosing CHA use can also facilitate better integration of CHA into both conventional care treatments and self-care.…”
mentioning
confidence: 99%
“…Despite the importance of CHA disclosure for safe and effective coordination of care, rates of disclosure to conventional care providers are not uniformly high, and can vary greatly across and within different populations. For example, rates of disclosure range from 21 to 71 % in general medical populations (16, 17), from 12 to 53 % in oncology patients (18, 19), and are as low as 36 % in HIV patients (20), and 30 % in hypertension patients (11). …”
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confidence: 99%
“…Although there is evidence that yoga provides reduction in OA symptoms (Cheung, Wyman, Resnick, & Savik, 2014), this is the first randomized controlled trial to examine the effect of CY among English-speaking and Spanish-speaking older adults with OA who are not able to participate in strenuous or standing exercise. It can be concluded that Sit ‘N’ Fit Chair Yoga is a linguistically sensitive mind-body program designed for older adults with OA that produces positive outcomes in biopsychosocial changes.…”
Section: Discussionmentioning
confidence: 99%
“…Phenolic compounds are reported to be responsible for reducing the lipid peroxidation and other types of oxidative process that leads to the generation of free radicals (Gulcin 2006; Yadav et al 2014). According to Hassan et al (2014) the extracts showing significant antioxidant activity are good antiangiogenic agents. The potential antiangiogenic activity of this endophytic extract may be attributed its antioxidant capacity and in turn to the phenolics and flavonoids.…”
Section: Discussionmentioning
confidence: 99%