Inhibition of tooth erosion by milk containing different fluoride concentrations: An in vitro study

Magalhães, Ana Carolina; Levy, Flávia Mauad; Souza, Beatriz Martines de; Cardoso, Cristiane de Almeida Baldini; Cassiano, Luiza Paula Silva; Pessan, Juliano Pelim; Buzalaf, Marília Afonso Rabelo

doi:10.1016/j.jdent.2013.12.009

Cited by 23 publications

(20 citation statements)

References 28 publications

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“…These results were different from those reported in our previous study [Magalhães et al, 2014]. The hypothesis to explain such differences between both studies is the fact that in the present study we had 19 treatments, a larger number of groups than in our previous work [Magalhães et al, 2014], reducing the probability of finding significant differences among them. Based on the results, we showed no dose-response effect in the present study and 10 ppm F seems to be the most effective F concentration against both enamel and dentine erosion.…”

Section: Discussioncontrasting

confidence: 97%

“…Similarly to Magalhães et al [2014], the present results also showed a beneficial effect of milk before the erosive challenge, especially for enamel (for dentine, only in the absence of F), which might be due to the protein content rather than fat, since there was no significant difference between whole and fat-free milk ( table 1 ). Milk casein has already been shown to have some protective effect against tooth erosion [Cheaib and Lussi, 2011;Nongonierma and Fitzgerald, 2012].…”

Section: Discussionsupporting

confidence: 79%

“…Another previous study demonstrated a beneficial effect of applying milk before an erosive challenge both to enamel and dentine, with the best effect found for dentine [Magalhães et al, 2014]. In addition, all F concentrations (2.5, 5.0 and 10.0 ppm F) had a positive effect on the prevention of enamel and dentine erosion when milk was applied after the erosive challenge.…”

Section: Discussionmentioning

confidence: 73%

“…To increase the protective potential of milk, fluoride was added and recently investigated against tooth erosion in vitro [Magalhães et al, 2014]. In this study, whole milk containing F (ranging between 2.5 and 10.0 ppm) was able to significantly reduce enamel and dentine erosion compared with whole non-F milk, but no dose-response was observed.…”

mentioning

confidence: 88%

“…The sample size was calculated based on data from our previous study [Magalhães et al, 2014]. A sample size of 11 and 5 would be needed for enamel and dentine, respectively, in order to find a significant difference between the negative control (0.9% NaCl) and milk containing no fluoride, considering an α value of 0.05 and 80% power.…”

Section: Fluoride Treatment and Ph Cycling Modelmentioning

confidence: 99%

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Protective Effect of Whole and Fat-Free Fluoridated Milk, Applied before or after Acid Challenge, against Dental Erosion

et al. 2016

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This study analysed in vitro the effect of milk against dental erosion, considering three factors: the type of milk (bovine whole/fat-free), the presence of different fluoride concentrations and the time of application (before/after erosive challenge). Bovine enamel (n = 15/group) and root dentine (n = 12/group) specimens were submitted to the following treatments: after the first erosive challenge - 0.9% NaCl solution (negative control), whole milk with 0, 2.5, 5.0 and 10.0 ppm F, fat-free milk with 0, 2.5, 5.0 and 10.0 ppm F, and 0.05% NaF solution (positive control); before the first erosive challenge - whole milk with 0, 2.5, 5.0 and 10.0 ppm F, fat-free milk with 0, 2.5, 5.0 and 10.0 ppm F, and 0.05% NaF solution (positive control). Specimens were submitted to demineralisation-remineralisation regimes 4 times/day for 5 days. The response variables were enamel and dentine loss (in micrometres). Data were analysed using Kruskal-Wallis/Dunn's test (p < 0.05). For enamel, whole milk containing 10 ppm F, applied before the erosive challenge, was the most protective treatment, but with no significant difference compared with the same treatment carried out after the erosive challenge. For dentine, whole fluoridated milk (all concentrations, after), fat-free 10 ppm F milk (after, before) and whole milk with or without F (except 2.5 ppm F, all before) significantly reduced dentine erosion. It seems that the presence of fluoride, especially at 10 ppm, is the most important factor in reducing dental erosion.

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Section: Discussioncontrasting

confidence: 97%