2014
DOI: 10.1111/odi.12221
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Infective endocarditis prophylaxis

Abstract: Antibiotic prophylaxis for infective endocarditis continues to be administered empirically, although its indications are ever more restrictive. Some expert committees have even suggested that antibiotic prophylaxis is unnecessary, rekindling the controversy between those who defend the scientific evidence and those working in clinical practice; in any case, this proposal will facilitate the undertaking of prospective placebo-controlled trials, so necessary to resolve this issue. In the meantime, the most prude… Show more

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Cited by 10 publications
(9 citation statements)
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References 20 publications
(22 reference statements)
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“…However, guidelines from other bodies such as the American Heart Association (AHA) and the European Society of Cardiology (ESD) still recommend using prophylactic antibiotics to prevent infective endocarditis in some patients with congenital heart defects . Dentists therefore are encouraged to consult the patient's cardiologist and to follow the guidelines applied in their region …”
Section: Discussionmentioning
confidence: 99%
“…However, guidelines from other bodies such as the American Heart Association (AHA) and the European Society of Cardiology (ESD) still recommend using prophylactic antibiotics to prevent infective endocarditis in some patients with congenital heart defects . Dentists therefore are encouraged to consult the patient's cardiologist and to follow the guidelines applied in their region …”
Section: Discussionmentioning
confidence: 99%
“…For instance, screening for Cnm + strains in patients undergoing major dental procedures may help to identify people who are at a greater risk of developing extra‐oral infections. While a questionable strategy, these patients could be advised to receive antibiotic prophylaxis (Biswas et al ., ; Diz Dios, ; Duval & Hoen, ). Although S. mutans infections can be effectively treated with penicillin (Baddour, ), invasion of non‐professional phagocytic cells may represent a novel strategy by which S. mutans can evade antibiotic treatment (Knoll et al ., ; Jung et al ., ; Foster et al ., ).…”
Section: Current Knowledge and Potential Gapsmentioning
confidence: 99%
“…[3] Several guidelines regarding IE prevention are available globally including, British Society for Antimicrobial Chemotherapy guidelines (BSAC) on 2006, National Institute for Health and Clinical Excellence guidelines (NICE) on 2008, European Society of Cardiology guidelines on 2009, the Australian guidelines, and the American Heart Association guidelines (AHA) on 2007; most of these guidelines recommended a more restrictive use of prophylaxis for IE. [4567] The BSAC guidelines reduced cardiac conditions in which prophylaxis indicated to the presence of prosthetic valves, a history of IE, and some congenital heart diseases. [8] AHA guidelines added another indication, valvulopathy in cardiac transplant recipients.…”
Section: Introductionmentioning
confidence: 99%