Multilocular Unicystic Ameloblastoma of Mandible

Abstract

Introduction. We report a rare case of unicystic ameloblastoma (UA) of mandible which showed multilocular radiolucency on the left side of mandible on radiographic examination which is very unusual, and the majority of the cases of UAs till date has been reported of unilocular radiolucency. On histopathological examination, an odontogenic cystic lining that proliferates that intraluminally resembling ameloblastomatous epithelium was observed, leading to a definitive diagnosis of unicystic ameloblastoma. Case Presentation. A 42-year-old male patient presented with a swelling on the left side of the mandible extending from 33 to 36. Radiographically, it showed a multilocular radiolucent lesion resembling odontogenic cyst; however, the final diagnosis was made on histopathological ground with the inclusion of radiological and clinical features. Conclusion. It can be concluded that at present, histopathologic examination is the most sensitive tool for differentiating between odontogenic cysts and UAs. However, both clinical and radiologic findings share equal contribution to the final diagnosis.

A Classic Case of Solid Multiloculated Ameloblastoma of the Mandible

“…3 The lesion may resemble an odontogenic keratocyst and sometimes the differentiation may be possible only on histopathological correlation. 4 There are, however, a few points which may aid in the differentiation radiologically. According to literature odontogenic keratocysts have lower CT density with higher heterogeneity than Ameloblastomas.…”

An Insight into the Histopathology of Oral Neoplasms with Basaloid Morphology and a Working Classification

“…29 The stellate reticulum-like cells are absent and central cells may be polyhedral. 28,29 The nuclear orientation of peripheral cells is different from the other histopathological patterns of ameloblastomas: they are usually cuboidal or columnar and do not show reverse polarity (Figure 4). BCAs show a close resemblance to BCC on histopathology; however a demarcation can be made on immunohistochemical grounds by using Ber-EP4.…”

“…28 Basal cell ameloblastoma is a rare variant of solid most reliable means of differentiation. Only 21 cases of IOBCC have been reported in the literature to date.…”

A Review of the Odontogenic Keratocyst and Report of a Case

“…Unicystic ameloblastoma and orthokeratinized odontogenic cyst (OOC) though present with the same clinical and radiographic features, Histologically Unicystic ameloblastoma has ameloblasticepithelial lining which is pathognomic of this cyst. The suprabasilar areas often loosen up giving the appearance like a stellate reticulum [15]. OKC shares similar characteristics with Orthokeratinized odontogenic cyst with respect to age of occurrence and site, yet these two lesions differ in their biological activity [16] OKC'S tend to grow in antero posterior direction within the medullary cavity of the bone and may cause an obvious bone expansion [13].…”